Mouse Anti-VAMP1 Monoclonal Antibody – Cat# MBS604641

Western Blot analysis of VAMP-1 using MBS604641 (0.2ug/ml). |30ug of whole cell extracts from exponentially growing human Daudi and HepG2 and mouse LI2 and BAF3 cells were prepared, resolved by SDS-PAGE, and transferred to a PVDF membrane.

VAMP 1 (VAMP1) Antibody – Mouse Monoclonal

Name: VAMP1 Antibody; Monoclonal; Mouse; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS604641
Price: 1030 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS604641

VAMP-1 (vesicle-associated membrane protein 1; also synaptobrevin-1/SYB1) is an 18kD member of the synaptobrevin family of proteins. It is expressed in neurons, neutrophils and skeletal muscle cells, and participates in vesicle fusion with the plasma… More details

$1030 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

VAMP 1 (Vamp1), Monoclonal Antibody

Full Product Name

VAMP 1 (Vesicle Associated Membrane Protein 1, Vesicle-associated Membrane Protein 1, VAMP1, VAMP-1, DKFZp686H12131, Synaptobrevin 1, Synaptobrevin-1, SYB1, SYB-1)

Product Gene Name

anti-Vamp1 antibody

Product Synonym Names

Anti -VAMP 1 (Vesicle Associated Membrane Protein 1, Vesicle-associated Membrane Protein 1, VAMP1, VAMP-1, DKFZp686H12131, Synaptobrevin 1, Synaptobrevin-1, SYB1, SYB-1)

Clonality

Monoclonal

Isotype

IgG1

Clone Number

9L863

Host

Mouse

Species Reactivity

Human, Mouse

Form/Format

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes endogenous human VAMP-1 and VAMP-2 at ~16kD. Does not react with recombinant VAMP family members 5, 7, 8. Species Crossreactivity: mouse.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C for short-term only. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

12,797 Da

Chromosome Location

Chromosome: 4; NC_005103.2 (161333661..161340447). Location: 4q42

3D Structure

ModBase 3D Structure for Q63666

Immunogen

E. coli-derived recombinant human VAMP-1 (aa1-96; Accession # P23763).

Hybridoma

Mouse myeloma cells with B cells obtained from a mouse immunized with purified, E. coli-derived, recombinant human VAMP-1 (aa1-96).

Product Categories/Family for anti-Vamp1 antibody

Antibodies; Abs to Membrane Proteins

Applications Tested/Suitable for anti-Vamp1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-Vamp1 antibody

Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.2ug/ml
Immunohistochemistry: 25ug/ml

Other Notes

Small volumes of anti-Vamp1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Vamp1 purchase

MBS604641 is an antibody targeting Vamp1. Also known as VAMP 1 (Vesicle Associated Membrane Protein 1, Vesicle-associated Membrane Protein 1, VAMP1, VAMP-1, DKFZp686H12131, Synaptobrevin 1, Synaptobrevin-1, SYB1, SYB-1). Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Vamp1. It may not necessarily be applicable to this product.

NCBI GI #

76443677

NCBI GeneID

25624

NCBI Accession #

NP_037222.2

UniProt Primary Accession #

Q63666

UniProt Secondary Accession #

O09025; Q56A22; Q8CH14; A6YSN3

UniProt Related Accession #

Q63666

GenBank Nucleotide #

NM_013090.2

NCBI Official Full Name

vesicle-associated membrane protein 1

NCBI Official Synonym Full Names

vesicle-associated membrane protein 1

NCBI Official Symbol

Vamp1

NCBI Official Synonym Symbols

Syb1

UniProt Protein Name

Vesicle-associated membrane protein 1

UniProt Synonym Protein Names

Synaptobrevin-1

Protein Family

Vesicle-associated membrane protein

UniProt Gene Name

Vamp1

UniProt Synonym Gene Names

Syb1

UniProt Entry Name

VAMP1_RAT

NCBI Protein Information

vesicle-associated membrane protein 1; VAMP-1; synaptobrevin 1; synaptobrevin-1

NCBI Summary for Vamp1

plays a role in protein transport to the plasma membrane [RGD]

UniProt Comments for Vamp1

VAMP1: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: SNARE complex; mitochondrial outer membrane; synaptic vesicle; cell surface; cytoplasmic vesicle membrane; synaptic vesicle membrane; mitochondrion; integral to membrane; terminal button; cytosol; cell junction

Molecular Function: SNAP receptor activity; protein binding; SNARE binding

Biological Process: vesicle-mediated transport; vesicle fusion; intracellular protein transport; exocytosis; neurotransmitter secretion

Research Articles on Vamp1

1. multiple domains outside the R-SNARE of tomosyn are critical to the efficacy of inhibition by tomosyn on exocytotic secretion

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Vamp1 antibody

Products by Pathway	Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with anti-Vamp1 antibody

Disease Name	Pubmed Publications
Schizophrenia Antibodies	>3 publications with Vamp1 and Schizophrenia
Central Nervous System Diseases Antibodies	>3 publications with Vamp1 and Central Nervous System Diseases
Wasting Syndrome Antibodies	>2 publications with Vamp1 and Wasting Syndrome
Dementia Antibodies	>2 publications with Vamp1 and Dementia
Mental Disorders Antibodies	>2 publications with Vamp1 and Mental Disorders
Hypertension Antibodies	>1 publications with Vamp1 and Hypertension
Pain Antibodies	>1 publications with Vamp1 and Pain
Cognition Disorders Antibodies	>1 publications with Vamp1 and Cognition Disorders
Inflammation Antibodies	>1 publications with Vamp1 and Inflammation

Organs/Tissues associated with anti-Vamp1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>26 publications with Vamp1 and Brain
Muscle Antibodies	>7 publications with Vamp1 and Muscle
Heart Antibodies	>5 publications with Vamp1 and Heart
Inner Ear Antibodies	>1 publications with Vamp1 and Inner Ear
Adrenal Gland Antibodies	>1 publications with Vamp1 and Adrenal Gland
Uncharacterized Tissue Antibodies	>1 publications with Vamp1 and Uncharacterized Tissue
Eye Antibodies	>1 publications with Vamp1 and Eye