Salinomycin

Salinomycin is a polyether ionophore with broad spectrum Gram +ve and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations, particularly potassium. Salinomycin is used in animal health for control of coccidia and for growth promotion in ruminants. Recently, salinomycin has been shown to inhibit cancer stem cells and is > 100 times more potent than taxol. While the mechanism of action is unknown, it was noted that among the 60,000 compounds screened, another monovalent ionophore, nigericin, and a chloride channel inhibitor, avermectin, were also active.

Small volumes of Salinomycin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS6047932 is a biochemical targeting Salinomycin. Host: Salinomycin from Streptomyces sp.