Mouse Anti-FCRLA Monoclonal Antibody – Cat# MBS605603

Blood-derived CD19+ lymphocytes were |stained with MBS605603 (filled |histogram) or isotype control open histogram, dotted line) |followed by APC-conjugated anti-mouse |antibody.

Fc Receptor-Like 5 (FCRLA) Antibody – Mouse Monoclonal

Name: FCRLA Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS605603
Price: 1090 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS605603

Fc receptor-like 5 (FCRL5), also known as FcRH5 and IRTA2, is a member of the Ig superfamily. It shares sequence homology with the classical Fc receptors for Ig and possesses cytoplasmic ITIM and ITAM-like motifs. Secreted variants and a GPI-anchored form of… More details

$1090 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fc Receptor-like 5 (FCRLA), Monoclonal Antibody

Full Product Name

Fc Receptor-like 5 (FCRL5, FcRH5)

Product Gene Name

anti-FCRLA antibody

Product Synonym Names

Anti -Fc Receptor-like 5 (FCRL5, FcRH5)

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

9H118

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human FCRL5.

Preparation and Storage

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

25,366 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (161676762..161684142). Location: 1q23.3

3D Structure

ModBase 3D Structure for Q5VXB1

Immunogen

NS0-derived, recombinant human FCRL5 aa16-844; AAK93971.

Product Categories/Family for anti-FCRLA antibody

Antibodies; Abs to Receptors

Applications Tested/Suitable for anti-FCRLA antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-FCRLA antibody

Dilution: Flow Cytometry: 25ug/ml
ELISA: 0.5-1.0ug/ml

Other Notes

Small volumes of anti-FCRLA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FCRLA purchase

MBS605603 is an antibody targeting FCRLA. Also known as Fc Receptor-like 5 (FCRL5, FcRH5). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FCRLA. It may not necessarily be applicable to this product.

NCBI GI #

296434268

NCBI GeneID

84824

NCBI Accession #

NP_001171801.1

UniProt Primary Accession #

Q5VXB1

UniProt Related Accession #

Q5VXA5; Q5VXB1; Q6MZF2; Q7L513

GenBank Nucleotide #

NM_001184872.1

NCBI Official Full Name

Fc receptor-like A isoform 5

NCBI Official Synonym Full Names

Fc receptor-like A

NCBI Official Symbol

FCRLA

NCBI Official Synonym Symbols

FCRL; FCRX; FREB; FCRL1; FCRLX; FCRLb; FCRLd; FCRLe; FCRLM1; FCRLc1; FCRLc2; MGC4595; RP11-474I16.5

UniProt Protein Name

Fc receptor-like A

Protein Family

Fc receptor

UniProt Gene Name

FCRLA

UniProt Entry Name

Q5VXB1_HUMAN

NCBI Protein Information

Fc receptor-like A; OTTHUMP00000032485; OTTHUMP00000032486; OTTHUMP00000032487; OTTHUMP00000032488; OTTHUMP00000032489; OTTHUMP00000032490; OTTHUMP00000032491; fc receptor-like protein; Fc receptor related protein X; fc receptor-related protein X; Fc receptor-like and mucin-like 1; fc receptor homolog expressed in B-cells; fc receptor-like and mucin-like protein 1; Fc receptor homolog expressed in B cells (FREB)

NCBI Summary for FCRLA

This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [supplied by RefSeq]

UniProt Comments for FCRLA

May be implicated in B-cell differentiation and lymphomagenesis.

Research Articles on FCRLA

1. The studies reported here demonstrate that FCRLA is more broadly expressed among human B lineage cells than originally reported; it is found at significant levels in resting blood B cells and at varying levels in all B-cell subsets in tonsil.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-FCRLA antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>6 publications with FCRLA and Neoplasms

Organs/Tissues associated with anti-FCRLA antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>10 publications with FCRLA and Blood
Tonsil Antibodies	>2 publications with FCRLA and Tonsil
Bone Marrow Antibodies	>2 publications with FCRLA and Bone Marrow
Spleen Antibodies	>1 publications with FCRLA and Spleen
Skin Antibodies	>1 publications with FCRLA and Skin