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VCX3A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS605618

VCX-A is only expressed in testis and may play a role in spermatogenesis or in sex ratio distortion. It is a 186aa peptide that has an estimated molecular weight of ~20kD. It was recently identified that VCX-A is an inhibitor of the decapping enzyme DCP2 and… More details

$750 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VCX-A (VCX3A), Monoclonal Antibody
Full Product Name
VCX-A (Variable charge X-linked protein 3, Variably charged protein X-A, VCX-8r, Variable charge protein on X with eight repeats, VCX3A, VCX3, VCX8R, VCXA)
Product Gene Name
Product Synonym Names
Anti -VCX-A (Variable charge X-linked protein 3, Variably charged protein X-A, VCX-8r, Variable charge protein on X with eight repeats, VCX3A, VCX3, VCX8R, VCXA)
Clonality
Monoclonal
Isotype
IgG
Clone Number
9G460
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes VCX-A. Species Crossreactivity: human, mouse, and rat.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degree C. Aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
20,020 Da
Chromosome Location
Chromosome: X; NC_000023.10 (6451659..6453159, complement). Location: Xp22
OMIM
300229
3D Structure
ModBase 3D Structure for Q9NNX9
Immunogen
Partial recombinant human VCX-A (aa2-100) with a GST tag.
Applications Tested/Suitable for anti-VCX3A antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-VCX3A antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-VCX3A antibody

Western blot detection of VCX-A expression in 293T transfected cell lysate (lane 1) and non-tranfected 293T lysate (lane 2).
Mouse Anti-VCX3A Monoclonal Antibody – Cat# MBS605618

Other Notes

Small volumes of anti-VCX3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VCX3A purchase

MBS605618 is an antibody targeting VCX3A. Also known as VCX-A (Variable charge X-linked protein 3, Variably charged protein X-A, VCX-8r, Variable charge protein on X with eight repeats, VCX3A, VCX3, VCX8R, VCXA). Reactive in Human, Mouse, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for VCX3A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
variable charge X-linked protein 3
NCBI Official Synonym Full Names
variable charge, X-linked 3A
NCBI Official Symbol
VCX3A
NCBI Official Synonym Symbols
VCX3; VCXA; VCX-A; VCX8R; VCX-8r
UniProt Protein Name
Variable charge X-linked protein 3
UniProt Synonym Protein Names
Variable charge protein on X with eight repeats; VCX-8r; Variably charged protein X-A
UniProt Gene Name
VCX3A
UniProt Synonym Gene Names
VCX3; VCX8R; VCXA; VCX-8r; VCX-A
UniProt Entry Name
VCX3_HUMAN
NCBI Protein Information
variable charge X-linked protein 3; variably charged X-A; variably charged protein X-A; variable charge protein on X with eight repeats

NCBI Summary for VCX3A

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]
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UniProt Comments for VCX3A

VCX3A: May mediate a process in spermatogenesis or may play a role in sex ratio distortion. Belongs to the VCX/VCY family.

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: nucleolus; nucleus

Biological Process: brain development

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VCX3A antibody

 Reference Product  PubMed Publications
 STS antibody  >4 publications with VCX3A and STS

Diseases associated with anti-VCX3A antibody

Organs/Tissues associated with anti-VCX3A antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with VCX3A and Skin
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