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Tissue Factor Pathway Inhibitor TFPI (TFPI) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS606041

TFPI is the main physiological inhibitor of the extrinsic coagulation pathway. It is a Kunitz-type serine protease inhibitor comprising three tandem units; the first and second units inhibit Factor VIIa/tissue factor complex and factor Xa respectively. More details

$950 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tissue Factor Pathway Inhibitor TFPI, Monoclonal Antibody
Full Product Name
Tissue Factor Pathway Inhibitor TFPI
Product Gene Name
Product Synonym Names
Anti -Tissue Factor Pathway Inhibitor TFPI
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9F646
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes TFPI
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
35,085 Da
Chromosome Location
Chromosome: 12; NC_007869.1 (51104687..51208491, complement)
3D Structure
ModBase 3D Structure for Q28864
Immunogen
Truncated TFPI (34kD)
Applications Tested/Suitable for anti-TFPI antibody
ELISA (EL/EIA)
Application Notes for anti-TFPI antibody
Suitable for use in ELISA.
Dilution: ELISA: 1:2000

Other Notes

Small volumes of anti-TFPI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TFPI purchase

MBS606041 is an antibody targeting TFPI. Also known as Tissue Factor Pathway Inhibitor TFPI. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TFPI. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tissue factor pathway inhibitor
NCBI Official Symbol
TFPI
NCBI Official Synonym Symbols
EPI; LACI
UniProt Protein Name
Tissue factor pathway inhibitor
UniProt Synonym Protein Names
Extrinsic pathway inhibitor; EPI; Lipoprotein-associated coagulation inhibitor
UniProt Gene Name
TFPI
UniProt Synonym Gene Names
TFPI1
UniProt Entry Name
TFPI1_MACMU
NCBI Protein Information
tissue factor pathway inhibitor; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor

UniProt Comments for TFPI

Function: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

Subcellular location: Secreted.

Domain: This inhibitor contains three inhibitory domains. The first domain interacts with VIIa and TF, the second one with Xa

Post-translational modification: O-glycosylated

Sequence similarities: Contains 3 BPTI/Kunitz inhibitor domains.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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