Mouse Anti-ITGB3 Monoclonal Antibody – Cat# MBS606138

Integrin Alphav Beta3 (ITGB3) Antibody – Mouse Monoclonal

Name: ITGB3 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS606138
Price: 980 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS606138

In cell matrix adhesions, clustered integrins (each made up of a noncovalently linked alpha and beta subunit) bind to endothelium cell matrix (ECM) components via their globular head domains. They connect to the actin cytoskeleton via adaptor proteins that… More details

$980 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Integrin alphaV beta3 (ITGB3), Monoclonal Antibody

Full Product Name

Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor) (FITC)

Product Gene Name

anti-ITGB3 antibody

Product Synonym Names

Anti -Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor) (FITC)

Clonality

Monoclonal

Isotype

IgG1

Clone Number

9G192

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 1% BSA, 0.02% sodium azide. Labeled with fluorescein isothiocyanate (FITC).

Purity/Purification

Affinity Purified
Purified.

Specificity

Recognizes human alpha-V/beta-3 integrin present on human endothelium cells.

Preparation and Storage

For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.

Chromosome Location

Chromosome: 12; NC_010454.3 (16718915..16775379, complement). Location: chromosome: 12

Immunogen

human Integrin, alphaV, beta3.

Product Categories/Family for anti-ITGB3 antibody

Antibodies; Abs to Vitronectin

Applications Tested/Suitable for anti-ITGB3 antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-ITGB3 antibody

Suitable for use in Flow Cytometry and Immunoassays..
Dilution: Flow Cytometry: 1:50

Other Notes

Small volumes of anti-ITGB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ITGB3 purchase

MBS606138 is an antibody targeting ITGB3. Also known as Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor) (FITC). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ITGB3. It may not necessarily be applicable to this product.

NCBI GI #

NCBI GeneID

NCBI Accession #

GenBank Nucleotide #

NCBI Official Full Name

integrin beta-3

NCBI Official Symbol

ITGB3

NCBI Official Synonym Symbols

CD61

Protein Family

Integrin

NCBI Protein Information

integrin beta-3; beta3 integrin; integrin beta 3; glycoprotein GPIIIa

Research Articles on ITGB3

1. The observed effects of shear stress on integrin alpha(v)beta(3) and p38 MAPK activation, as well as on FGF-2 release could be mimicked by application of pancreatic elastase to static endothelial cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ITGB3 antibody

Products by Pathway	Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Dilated Cardiomyopathy Pathway antibodies	Dilated Cardiomyopathy Pathway Diagram
Dilated Cardiomyopathy Pathway antibodies	Dilated Cardiomyopathy Pathway Diagram
ECM Proteoglycans Pathway antibodies	ECM Proteoglycans Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
Elastic Fibre Formation Pathway antibodies	Elastic Fibre Formation Pathway Diagram