Mouse Anti-JUND Monoclonal Antibody – Cat# MBS606800

JUND Antibody – Mouse Monoclonal

Name: JUND Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS606800
Price: 1045 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS606800

JunD is a member of the Jun family of nuclear transcription factors. It dimerizes with other Jun or More details

$1045 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

JunD, Monoclonal Antibody

Full Product Name

JunD (Jun D proto-oncogene, AP-1, Transcription factor jun-D)

Product Gene Name

anti-JUND antibody

Product Synonym Names

Anti -JunD (Jun D proto-oncogene, AP-1, Transcription factor jun-D)

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

9H99

Host

Mouse

Form/Format

Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human/mouse JunD at ~45kD.

Preparation and Storage

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

35,174 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (18390563..18392432, complement). Location: 19p13.2

OMIM

165162

3D Structure

ModBase 3D Structure for P17535

Immunogen

Recombinant human JunD, aa47-156; P17535 (E. coli).

Product Categories/Family for anti-JUND antibody

Antibodies; Abs to Transcription Factors

Applications Tested/Suitable for anti-JUND antibody

Western Blot (WB)

Application Notes for anti-JUND antibody

Suitable for use in Western Blot.
Dilution: Western Blot: 1ug/ml

Other Notes

Small volumes of anti-JUND antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JUND purchase

MBS606800 is an antibody targeting JUND. Also known as JunD (Jun D proto-oncogene, AP-1, Transcription factor jun-D). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for JUND. It may not necessarily be applicable to this product.

NCBI GI #

34019

NCBI GeneID

3727

UniProt Primary Accession #

P17535

UniProt Secondary Accession #

Q53EK9

UniProt Related Accession #

P17535

NCBI Official Full Name

junD protein

NCBI Official Synonym Full Names

jun D proto-oncogene

NCBI Official Symbol

JUND

NCBI Official Synonym Symbols

AP-1

UniProt Protein Name

Transcription factor jun-D

Protein Family

Transcription factor

UniProt Gene Name

JUND

UniProt Entry Name

JUND_HUMAN

NCBI Protein Information

transcription factor jun-D; JunD-FL isoform; activator protein 1

NCBI Summary for JUND

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. [provided by RefSeq]

UniProt Comments for JUND

JunD: Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily.

Protein type: Transcription factor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleoplasm; protein complex; chromatin; nucleus

Molecular Function: ligand-dependent nuclear receptor binding; protein binding; enzyme binding; sequence-specific DNA binding; double-stranded DNA binding; transcription factor activity

Biological Process: circadian rhythm; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; response to peptide hormone stimulus; response to light stimulus; positive regulation of osteoblast differentiation; response to mechanical stimulus; positive regulation of transcription from RNA polymerase II promoter; response to lipopolysaccharide; response to organic cyclic substance; aging; osteoblast development

Research Articles on JUND

1. These results suggest that the induction of MMP-7 by Tax is regulated by JunD and that MMP-7 could facilitate visceral invasion in adult T-cell leukemia .

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-JUND antibody

Reference Product	PubMed Publications
FOS antibody	>479 publications with JUND and FOS
FOSB antibody	>163 publications with JUND and FOSB
MEN1 antibody	>42 publications with JUND and MEN1
FOSL2 antibody	>34 publications with JUND and FOSL2
SMAD3 antibody	>17 publications with JUND and SMAD3
MAPK3 antibody	>12 publications with JUND and MAPK3
MAPK8 antibody	>11 publications with JUND and MAPK8
MAPK1 antibody	>11 publications with JUND and MAPK1
SMAD4 antibody	>9 publications with JUND and SMAD4
NFE2L2 antibody	>8 publications with JUND and NFE2L2

Pathways associated with anti-JUND antibody

Products by Pathway	Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
EGFR1 Signaling Pathway antibodies	EGFR1 Signaling Pathway Diagram
Hypertrophy Model Pathway antibodies	Hypertrophy Model Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
TGF-beta Receptor Signaling Pathway antibodies	TGF-beta Receptor Signaling Pathway Diagram
Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway antibodies	Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway Diagram

Diseases associated with anti-JUND antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>228 publications with JUND and Neoplasms
Carcinoma Antibodies	>60 publications with JUND and Carcinoma
Leukemia Antibodies	>51 publications with JUND and Leukemia
Cell Transformation, Neoplastic Antibodies	>47 publications with JUND and Cell Transformation, Neoplastic
Necrosis Antibodies	>43 publications with JUND and Necrosis
Inflammation Antibodies	>34 publications with JUND and Inflammation
Adenocarcinoma Antibodies	>31 publications with JUND and Adenocarcinoma
Endocrine Gland Neoplasms Antibodies	>30 publications with JUND and Endocrine Gland Neoplasms
Lymphoma Antibodies	>27 publications with JUND and Lymphoma
Leukemia, T-Cell Antibodies	>27 publications with JUND and Leukemia, T-Cell

Organs/Tissues associated with anti-JUND antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>101 publications with JUND and Blood
Brain Antibodies	>89 publications with JUND and Brain
Bone Antibodies	>56 publications with JUND and Bone
Liver Antibodies	>48 publications with JUND and Liver
Muscle Antibodies	>40 publications with JUND and Muscle
Lung Antibodies	>33 publications with JUND and Lung
Skin Antibodies	>31 publications with JUND and Skin
Vascular Antibodies	>26 publications with JUND and Vascular
Kidney Antibodies	>21 publications with JUND and Kidney
Prostate Antibodies	>18 publications with JUND and Prostate