Mouse Anti-ENTPD6 Monoclonal Antibody – Cat# MBS607752

ENTPD6 Antibody – Mouse Monoclonal

Name: ENTPD6 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS607752
Price: 980 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS607752

Ectonucleoside triphosphate diphosphohydrolase-6 (CD39L2), also known as rhCD39L2 /ENTPD6, is a secreted nucleoside phosphohydrolase, which catalyzes the hydrolysis of extracellular nucleotides, such as nucleoside 5'-diphosphates and nucleoside… More details

$980 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD39L2 (ENTPD6), Monoclonal Antibody

Full Product Name

CD39L2 (ENTPD6, Ectonucleoside Triphosphate Diphosphohydrolase 6)

Product Gene Name

anti-ENTPD6 antibody

Product Synonym Names

Anti -CD39L2 (ENTPD6, Ectonucleoside Triphosphate Diphosphohydrolase 6)

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

9H88

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human CD39L2.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

53,246 Da

Chromosome Location

Chromosome: 20; NC_000020.10 (25176339..25207360). Location: 20p11.21

OMIM

603160

3D Structure

ModBase 3D Structure for O75354

Immunogen

Recombinant protein corresponding to aa61-484 from human CD39L2 lumenal domain expressed in CHO cell cells (O75354). Species Sequence Homology: chimpanzee; 99%, mouse; 88%, canine; 87%

Product Categories/Family for anti-ENTPD6 antibody

Antibodies; Abs to Enzymes

Applications Tested/Suitable for anti-ENTPD6 antibody

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)

Application Notes for anti-ENTPD6 antibody

Suitable for use in Direct ELISA, Western Blot and Immunoprecipitation.
Dilution: Direct ELISA: 0.5-1.0ug/ml. The detection limit for recombinant human CD39L2 is ~1ng/well.
Western Blot: 1-2ug/ml. The detection limit for recombinant human CD39L2 is ~20ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity 5 to 50 fold.
Immunoprecipitation: 25ug/ml to immunoprecipitate recombinant human CD39L2 from conditioned cell culture medium.

Other Notes

Small volumes of anti-ENTPD6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENTPD6 purchase

MBS607752 is an antibody targeting ENTPD6. Also known as CD39L2 (ENTPD6, Ectonucleoside Triphosphate Diphosphohydrolase 6). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ENTPD6. It may not necessarily be applicable to this product.

NCBI GI #

3335098

NCBI GeneID

955

UniProt Primary Accession #

O75354

UniProt Secondary Accession #

Q5QPJ5; Q7Z5B5; Q8N3H3; Q8TAS7; Q9UJD1

UniProt Related Accession #

O60670; O75354; Q5QPI6; Q5QPJ0; Q5QPJ2; Q5QPJ4; Q5QPJ6

NCBI Official Full Name

CD39L2

NCBI Official Synonym Full Names

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

NCBI Official Symbol

ENTPD6

NCBI Official Synonym Symbols

CD39L2; IL6ST2; IL-6SAG; FLJ36711; NTPDase-6; dJ738P15.3; DKFZp781G2277; DKFZp781K21102

UniProt Protein Name

Ectonucleoside triphosphate diphosphohydrolase 6

UniProt Synonym Protein Names

CD39 antigen-like 2

Protein Family

Ectonucleoside triphosphate diphosphohydrolase

UniProt Gene Name

ENTPD6

UniProt Synonym Gene Names

CD39L2; IL6ST2

UniProt Entry Name

ENTP6_HUMAN

NCBI Protein Information

ectonucleoside triphosphate diphosphohydrolase 6; NTPDase 6; CD39-like 2; OTTHUMP00000030474; OTTHUMP00000030475; OTTHUMP00000030478; OTTHUMP00000030479; OTTHUMP00000030483; OTTHUMP00000030484; OTTHUMP00000030485; OTTHUMP00000030486; OTTHUMP00000030487; CD39 antigen-like 2; interleukin 6 signal transducer-2; ectonucleoside triphosphate diphosphohydrolase 6 (putative function)

NCBI Summary for ENTPD6

ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which is characteristic of NTPases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

UniProt Comments for ENTPD6

ENTPD6: Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5'-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 3.6.1.6; Hydrolase; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 20p11.21

Cellular Component: Golgi membrane; extracellular space; cell surface; integral to membrane; plasma membrane

Molecular Function: nucleoside-triphosphatase activity; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; uridine-diphosphatase activity

Biological Process: response to magnesium ion; metabolic process; response to calcium ion

Research Articles on ENTPD6

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ENTPD6 antibody

Products by Pathway	Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram

Diseases associated with anti-ENTPD6 antibody

Disease Name	Pubmed Publications
Gonadal Disorders Antibodies	>1 publications with ENTPD6 and Gonadal Disorders
Urogenital Neoplasms Antibodies	>1 publications with ENTPD6 and Urogenital Neoplasms
Seminoma Antibodies	>1 publications with ENTPD6 and Seminoma

Organs/Tissues associated with anti-ENTPD6 antibody

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>1 publications with ENTPD6 and Heart
Muscle Antibodies	>1 publications with ENTPD6 and Muscle
Blood Antibodies	>1 publications with ENTPD6 and Blood
Pancreas Antibodies	>1 publications with ENTPD6 and Pancreas
Nerve Antibodies	>1 publications with ENTPD6 and Nerve
Testis Antibodies	>1 publications with ENTPD6 and Testis