Mouse Anti-Glutamic Acid Decarboxylase Monoclonal Antibody – Cat# MBS607899

Immunohistochemical staining of GAD in rat hippocampus using MBS607899.

Glutamic Acid Decarboxylase Antibody – Mouse Monoclonal

Name: Glutamic Acid Decarboxylase Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS607899
Price: 1185 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS607899

The enzyme glutamic acid decarboxylase (GAD) catalyzes the synthesis of g-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. GAD is the rate-limiting enzyme in the biosynthesis of GABA from L-glutamic acid, and it… More details

$1185 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Glutamic Acid Decarboxylase, Monoclonal Antibody

Full Product Name

Glutamic Acid Decarboxylase (GAD)

Product Synonym Names

Anti -Glutamic Acid Decarboxylase (GAD)

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

2Q61

Host

Mouse

Species Reactivity

Rat

Form/Format

Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with 100ul sterile 40-50% glycerol, ddH2O.

Purity/Purification

Purified
Purified immunoglobulin

Specificity

Recognizes the lower MW isoform (65kDa) of the two GAD isoforms identified in brain. This monclonal antibody can be used for immunohistochemical localization in brain or pancreas. Has been used to label purified GAD on Western blots.

Preparation and Storage

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol, ddH2O and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunogen

Purified rat brain glutamic acid decarboxylase (GAD).

Product Categories/Family for anti-Glutamic Acid Decarboxylase antibody

Antibodies; Abs to Enzymes; Decarboxylase

Applications Tested/Suitable for anti-Glutamic Acid Decarboxylase antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-Glutamic Acid Decarboxylase antibody

Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry: 1ug/ml

Other Notes

Small volumes of anti-Glutamic Acid Decarboxylase antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Glutamic Acid Decarboxylase purchase

MBS607899 is an antibody targeting Glutamic Acid Decarboxylase. Also known as Glutamic Acid Decarboxylase (GAD). Reactive in Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Glutamic Acid Decarboxylase. It may not necessarily be applicable to this product.

NCBI GI #

182942

NCBI Official Full Name

glutamic acid decarboxylase

Protein Family

Glutamate decarboxylase

UniProt Comments for Glutamic Acid Decarboxylase

GAD2: Catalyzes the production of GABA. Homodimer. Belongs to the group II decarboxylase family.

Protein type: Other Amino Acids Metabolism - taurine and hypotaurine; Carbohydrate Metabolism - butanoate; EC 4.1.1.15; Lyase; Amino Acid Metabolism - alanine, aspartate and glutamate; Other Amino Acids Metabolism - beta-alanine

Chromosomal Location of Human Ortholog: 10p11.23

Cellular Component: Golgi membrane; presynaptic membrane; synaptic vesicle membrane; axon; perinuclear region of cytoplasm; plasma membrane; cytosol; cell junction

Molecular Function: protein binding; glutamate binding; glutamate decarboxylase activity; protein heterodimerization activity; pyridoxal phosphate binding

Biological Process: response to drug; synaptic transmission; glutamate decarboxylation to succinate; neurotransmitter secretion; neurotransmitter biosynthetic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Glutamic Acid Decarboxylase antibody

Reference Product	PubMed Publications
FLNA antibody	>12 publications with Glutamic Acid Decarboxylase and FLNA

Pathways associated with anti-Glutamic Acid Decarboxylase antibody

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Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram
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Organs/Tissues associated with anti-Glutamic Acid Decarboxylase antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>13 publications with Glutamic Acid Decarboxylase and Bone
Connective Tissue Antibodies	>4 publications with Glutamic Acid Decarboxylase and Connective Tissue
Heart Antibodies	>3 publications with Glutamic Acid Decarboxylase and Heart
Muscle Antibodies	>3 publications with Glutamic Acid Decarboxylase and Muscle
Brain Antibodies	>3 publications with Glutamic Acid Decarboxylase and Brain
Vascular Antibodies	>2 publications with Glutamic Acid Decarboxylase and Vascular
Embryonic Tissue Antibodies	>2 publications with Glutamic Acid Decarboxylase and Embryonic Tissue
Ear Antibodies	>1 publications with Glutamic Acid Decarboxylase and Ear
Kidney Antibodies	>1 publications with Glutamic Acid Decarboxylase and Kidney
Umbilical Cord Antibodies	>1 publications with Glutamic Acid Decarboxylase and Umbilical Cord