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Polycystin-1l2 (PKD1L2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS608070

Polycystin-1L2 may function as an ion-channel regulator and as a G-protein-coupled receptor. It is a multi-pass transmembrane protein that is expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. The highest… More details

$690 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Polycystin-1L2 (PKD1L2), Monoclonal Antibody
Full Product Name
Polycystin-1L2 (Polycystic kidney disease protein 1-like 2, PC1-like 2 Protein, PKD1L2, KIAA1879, PC1L2)
Product Gene Name
Product Synonym Names
Anti -Polycystin-1L2 (Polycystic kidney disease protein 1-like 2, PC1-like 2 Protein, PKD1L2, KIAA1879, PC1L2)
Clonality
Monoclonal
Isotype
IgG
Clone Number
9G416
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes human Polycystin-1L2.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degree C. Aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
12,851 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (81134484..81253975, complement). Location: 16q23.2
3D Structure
ModBase 3D Structure for Q6AI51
Immunogen
Recombinant human Polycystin-1L2, isoform 4 (1-306), with a GST tag.
Applications Tested/Suitable for anti-PKD1L2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-PKD1L2 antibody
Suitable for use in Western Blot and ELISA.

Western Blot (WB) of anti-PKD1L2 antibody

Western blot detection of human Polycystin-1L2 in HeLa cell lysate.
Mouse Anti-PKD1L2 Monoclonal Antibody – Cat# MBS608070

Other Notes

Small volumes of anti-PKD1L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PKD1L2 purchase

MBS608070 is an antibody targeting PKD1L2. Also known as Polycystin-1L2 (Polycystic kidney disease protein 1-like 2, PC1-like 2 Protein, PKD1L2, KIAA1879, PC1L2). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PKD1L2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
polycystic kidney disease protein 1-like 2 isoform c
NCBI Official Synonym Full Names
polycystic kidney disease 1-like 2
NCBI Official Symbol
PKD1L2
NCBI Official Synonym Symbols
PC1L2; FLJ45333; DKFZp686J19100
UniProt Protein Name
Putative uncharacterized protein DKFZp686J19100
UniProt Gene Name
DKFZp686J19100
UniProt Entry Name
Q6AI51_HUMAN
NCBI Protein Information
polycystic kidney disease protein 1-like 2; polycystin-1L2; OTTHUMP00000231959; OTTHUMP00000231961; PC1-like 2 protein

NCBI Summary for PKD1L2

This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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UniProt Comments for PKD1L2

PKD1L2: May function as an ion-channel regulator. May function as a G-protein-coupled receptor. Belongs to the polycystin family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16q23.2

Cellular Component: integral to membrane

Molecular Function: calcium ion binding; carbohydrate binding

Biological Process: ion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-PKD1L2 antibody

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