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SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6082770

Cell permeable. Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is… More details

$450 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMER28, Biochemical
Full Product Name
SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline)
Form/Format
Supplied as an off-white solid.
Purity/Purification
Highly Purified
~98% (TLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~264.12
CAS Number
307538-42-7
Molecular Formula
C??H??BrN?
Solubility
DMSO (~8mg/ml), EtOH (~2mg/ml)

Other Notes

Small volumes of SMER28 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMER28 purchase

MBS6082770 is a biochemical targeting SMER28. Also known as SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline).
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