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Galanin (GAL) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS608714

Galanin is a 29-amino acid peptide widely distributed in the peripheral and central nervous systems. In the brain, the highest concentrations are observed in the hypothalamus and particularly in the nerve terminals of the median eminence. It contracts smooth… More details

$700 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Galanin, Monoclonal Antibody
Full Product Name
Galanin (GAL, GAL1, GALN, GLNN)
Product Gene Name
anti-GAL antibody
Product Synonym Names
Anti -Galanin (GAL, GAL1, GALN, GLNN)
Clonality
Monoclonal
Isotype
IgG
Clone Number
9G360
Host
Mouse
Species Reactivity
Hamster, Mouse
Form/Format
Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 50ul sterile ddH2O.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes human Galanin at ~39kD. Species Crossreactivity: mouse.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Molecular Weight
13,302 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (68451983..68458643). Location: 11q13.3
OMIM
137035
3D Structure
ModBase 3D Structure for P22466
Immunogen
Recombinant human Galanin with a GST tag.

Product Categories/Family for anti-GAL antibody

Antibodies; Abs to Lectins
Applications Tested/Suitable for anti-GAL antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-GAL antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-GAL antibody

Western blot detection of GST tagged recombinant human Galanin. MBS608714 detects a band of ~39kD molecular weight. Note the GST tag alone is 26kD.
Mouse Anti-GAL Monoclonal Antibody – Cat# MBS608714

Other Notes

Small volumes of anti-GAL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAL purchase

MBS608714 is an antibody targeting GAL. Also known as Galanin (GAL, GAL1, GALN, GLNN). Reactive in Hamster, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GAL. It may not necessarily be applicable to this product.

NCBI GI #
1247490
NCBI GeneID
51083
UniProt Primary Accession #
P22466
UniProt Secondary Accession #
Q14413
UniProt Related Accession #
P22466; Q9Y2S1
NCBI Official Full Name
galanin
NCBI Official Synonym Full Names
galanin prepropeptide
NCBI Official Symbol
GAL
NCBI Official Synonym Symbols
GALN; GLNN; GMAP; MGC40167
UniProt Protein Name
Galanin peptides
Protein Family
Galactose 1-dehydrogenase
UniProt Gene Name
GAL
UniProt Synonym Gene Names
GAL1; GALN; GLNN
UniProt Entry Name
GALA_HUMAN
NCBI Protein Information
galanin peptides; OTTHUMP00000237192; galanin-related peptide; galanin-message-associated peptide

NCBI Summary for GAL

Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).[supplied by OMIM]

UniProt Comments for GAL

Galanin: Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion. Belongs to the galanin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: Golgi apparatus; extracellular space; cell soma; extracellular region; secretory granule

Molecular Function: type 3 galanin receptor binding; neuropeptide hormone activity; protein binding; type 2 galanin receptor binding; type 1 galanin receptor binding

Biological Process: response to drug; nervous system development; positive regulation of cortisol secretion; positive regulation of apoptosis; positive regulation of catagen; response to insulin stimulus; negative regulation of lymphocyte proliferation; cAMP-mediated signaling; insulin secretion; response to estrogen stimulus; neuropeptide signaling pathway; regulation of glucocorticoid metabolic process; positive regulation of transcription from RNA polymerase II promoter; feeding behavior; inflammatory response

Disease: Epilepsy, Familial Temporal Lobe, 8
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Research Articles on GAL

1. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GAL antibody

 Reference Product  PubMed Publications
 GALR1 antibody  >39 publications with GAL and GALR1
 GALR2 antibody  >36 publications with GAL and GALR2

Pathways associated with anti-GAL antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with anti-GAL antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1842 publications with GAL and Neoplasms
 Female Urogenital Diseases Antibodies  >506 publications with GAL and Female Urogenital Diseases
 Liver Diseases Antibodies  >435 publications with GAL and Liver Diseases
 Male Urogenital Diseases Antibodies  >424 publications with GAL and Male Urogenital Diseases
 Inflammation Antibodies  >382 publications with GAL and Inflammation
 Adenocarcinoma Antibodies  >342 publications with GAL and Adenocarcinoma
 Intestinal Neoplasms Antibodies  >216 publications with GAL and Intestinal Neoplasms
 Liver Neoplasms Antibodies  >197 publications with GAL and Liver Neoplasms
 Pain Antibodies  >157 publications with GAL and Pain
 Neurodegenerative Diseases Antibodies  >144 publications with GAL and Neurodegenerative Diseases

Organs/Tissues associated with anti-GAL antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3301 publications with GAL and Blood
 Brain Antibodies  >1365 publications with GAL and Brain
 Nerve Antibodies  >588 publications with GAL and Nerve
 Lung Antibodies  >583 publications with GAL and Lung
 Bone Antibodies  >509 publications with GAL and Bone
 Intestine Antibodies  >427 publications with GAL and Intestine
 Embryonic Tissue Antibodies  >348 publications with GAL and Embryonic Tissue
 Ovary Antibodies  >226 publications with GAL and Ovary
 Stomach Antibodies  >192 publications with GAL and Stomach
 Connective Tissue Antibodies  >180 publications with GAL and Connective Tissue
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