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FOLR2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS609209

The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FOLR2, Monoclonal Antibody
Full Product Name
FOLR2 (Folate Receptor beta, FR-beta, Folate Receptor 2 Folate Receptor, Fetal/Placental Placental Folate-binding Protein, FBP)
Product Gene Name
Product Synonym Names
Anti -FOLR2 (Folate Receptor beta, FR-beta, Folate Receptor 2 Folate Receptor, Fetal/Placental Placental Folate-binding Protein, FBP)
Immunogen Sequence
HHKTKPGPED KLHDQCSPWK KNACCTASTS QELHKDTSRL YNFNWDHCGK MEPACKRHFI QDTCLYECSP NLGPWIQQVN QTWRKERFLD VPL*
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4B12
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.4
Purity/Purification
Purified
Concentration
0.43mg/ml (lot specific)
Specificity
Recognizes human FOLR2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
29,280 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (71927819..71932994). Location: 11q13.3-q13.5
OMIM
136425
3D Structure
ModBase 3D Structure for P14207
Immunogen
Recombinant protein corresponding to aa36-128 from FOLR2 with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-FOLR2 antibody

Applications Tested/Suitable for anti-FOLR2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-FOLR2 antibody
Sandwich ELISA: The detetion limit for recombinant GST tagged FOLR2 is ~1ng/ml using MBS609209 as a capture antibody.
Western Blot: Detects a band at ~36.34kD using immunogen protein lysate.

Optimal dilutions to be determined by the researcher.

Western Blot (WB) of anti-FOLR2 antibody

Western Blot detection against Immunogen using MBS609209 (35.97kD) .
Mouse Anti-FOLR2 Monoclonal Antibody – Cat# MBS609209

Testing Data of anti-FOLR2 antibody

Detection limit for recombinant GST tagged FOLR2 is approximately 1ng/ml using MBS609209 as a capture antibody.
Mouse Anti-FOLR2 Monoclonal Antibody, Testing Data – Cat# MBS609209

Other Notes

Small volumes of anti-FOLR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOLR2 purchase

MBS609209 is an antibody targeting FOLR2. Also known as FOLR2 (Folate Receptor beta, FR-beta, Folate Receptor 2 Folate Receptor, Fetal/Placental Placental Folate-binding Protein, FBP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FOLR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
folate receptor beta
NCBI Official Synonym Full Names
folate receptor 2 (fetal)
NCBI Official Symbol
FOLR2
NCBI Official Synonym Symbols
FBP; FR-P3; FR-BETA; BETA-HFR; FBP/PL-1
UniProt Protein Name
Folate receptor beta
UniProt Synonym Protein Names
Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein
Protein Family
UniProt Gene Name
FOLR2
UniProt Synonym Gene Names
FR-beta; FBP
UniProt Entry Name
FOLR2_HUMAN
NCBI Protein Information
folate receptor beta; folate receptor, beta; folate receptor, fetal/placental; placental folate-binding protein; folate-binding protein, fetal/placental

UniProt Comments for FOLR2

FOLR2: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Belongs to the folate receptor family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 11q13.3-q13.5

Cellular Component: anchored to external side of plasma membrane; membrane; extracellular region

Molecular Function: folic acid transporter activity; folic acid binding

Biological Process: folic acid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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