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NKR2B4 (CD244) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS609436

The glycoprotein NKR2B4 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. More details

$1170 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NKR2B4 (CD244), Monoclonal Antibody
Full Product Name
NKR2B4 (Natural Killer Cell Receptor 2B4, NK Cell Type I Receptor Protein 2B4, 2B4, CD244 Molecule Natural Killer Cell Receptor 2B4, h2B4, CD244, NK Cell Activation Inducing Ligand, NAIL, Nmrk, SLAMF4)
Product Gene Name
Product Synonym Names
Anti -NKR2B4 (Natural Killer Cell Receptor 2B4, NK Cell Type I Receptor Protein 2B4, 2B4, CD244 Molecule Natural Killer Cell Receptor 2B4, h2B4, CD244, NK Cell Activation Inducing Ligand, NAIL, Nmrk, SLAMF4)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10B1117
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.4. No preservative added.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human natural killer receptor 2B4 (NKR2B4).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
2,243 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (160799950..160832692, complement). Location: 1q23.3
3D Structure
ModBase 3D Structure for Q96RQ2
Immunogen
CD244 Fusion protein.
Hybridoma
NS-1 myeloma cells with spleen cells from Balb/c mice.

Product Categories/Family for anti-CD244 antibody

Applications Tested/Suitable for anti-CD244 antibody
Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes for anti-CD244 antibody
Suitable for use in Flow Cytometry and Immunoprecipitation.
Dilution: Flow Cytometry: 1:50-1:200; 10ul labels 10e6 cells in 100ul

Testing Data of anti-CD244 antibody

Staining of human peripheral blood lymphocytes with MBS609436.
Mouse Anti-CD244 Monoclonal Antibody – Cat# MBS609436

Testing Data of anti-CD244 antibody

Mouse Anti-CD244 Monoclonal Antibody, Testing Data – Cat# MBS609436

Testing Data of anti-CD244 antibody

Mouse Anti-CD244 Monoclonal Antibody, Testing Data – Cat# MBS609436

Testing Data of anti-CD244 antibody

Mouse Anti-CD244 Monoclonal Antibody, Testing Data – Cat# MBS609436

Other Notes

Small volumes of anti-CD244 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD244 purchase

MBS609436 is an antibody targeting CD244. Also known as NKR2B4 (Natural Killer Cell Receptor 2B4, NK Cell Type I Receptor Protein 2B4, 2B4, CD244 Molecule Natural Killer Cell Receptor 2B4, h2B4, CD244, NK Cell Activation Inducing Ligand, NAIL, Nmrk, SLAMF4). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD244. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
natural killer cell receptor 2B4 isoform 3
NCBI Official Synonym Full Names
CD244 molecule, natural killer cell receptor 2B4
NCBI Official Symbol
CD244
NCBI Official Synonym Symbols
2B4; NAIL; Nmrk; NKR2B4; SLAMF4
UniProt Protein Name
Natural killer cell receptor 2B4
UniProt Entry Name
Q96RQ2_HUMAN
NCBI Protein Information
natural killer cell receptor 2B4; h2B4; OTTHUMP00000027884; OTTHUMP00000027885; OTTHUMP00000027886; OTTHUMP00000027887; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; NK cell activation inducing ligand NAIL

NCBI Summary for CD244

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt Comments for CD244

CD244: Modulate other receptor-ligand interactions to enhance leukocyte activation. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: blood coagulation; signal transduction; leukocyte migration

Disease: Rheumatoid Arthritis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD244 antibody

Diseases associated with anti-CD244 antibody

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