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XAV939 (3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6096554

A Tankyrase (TNKS) inhibitor (IC50 = 110nM for TNKS1 and 4nM for TNKS2). Antagonizes wnt signaling via stimulation of beta-catenin degradation and stabilization of axin. Inhibits proliferation of the mu-catenin-dependent colon carcinoma cell line DLD-1. More details

$430 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
XAV939, Biochemical
Full Product Name
XAV939 (3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one)
Form/Format
Supplied as a white solid. Reconstitute with 50mM DMSO.
Purity/Purification
Highly Purified
~98% (HPLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer
Molecular Weight
312.31
CAS Number
284028-89-3
Molecular Formula
C14H11F3N2OS

Product Categories/Family for XAV939 biochemical

Biochemicals; Biochem-Inhibitors

Structure of XAV939 biochemical

Structure of XAV939.
XAV939 (3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one) Biochemical – Cat# MBS6096554

Other Notes

Small volumes of XAV939 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XAV939 purchase

MBS6096554 is a biochemical targeting XAV939. Also known as XAV939 (3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one).
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