Mouse Anti-CLEC4D Monoclonal Antibody – Cat# MBS609773

CLEC4D Antibody – Mouse Monoclonal

Name: CLEC4D Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS609773
Price: 980 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS609773

CLEC4D (C-type lectin domain family 4 member D), also known as CLCSF8, CLEC-6, and MCL, is a 30kD type II transmembrane (TM) glycoprotein that belongs to the CLR (C-type Lectin Receptor) family of molecules. It is synthesized as a 215aa protein that contains… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CLEC4D, Monoclonal Antibody

Full Product Name

CLEC4D (C-type Lectin Domain Family 4, Member D, C-type Lectin Superfamily Member 8, C-type Lectin-like Receptor 6, CLEC-6, CLECSF8, MCL)

Product Gene Name

anti-CLEC4D antibody

Product Synonym Names

Anti -CLEC4D (C-type Lectin Domain Family 4, Member D, C-type Lectin Superfamily Member 8, C-type Lectin-like Receptor 6, CLEC-6, CLECSF8, MCL)

Clonality

Monoclonal

Isotype

IgG2B

Clone Number

10K53

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human CLEC4D. Species sequence homology: mouse (63%).

Preparation and Storage

May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.

Molecular Weight

24,704 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (8666136..8674962). Location: 12p13.31

OMIM

609964

3D Structure

ModBase 3D Structure for Q8WXI8

Immunogen

Purified, NS0-derived, recombinant human CLEC4D (aa52-215; Accession #Q8WXI8).

Hybridoma

Fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human CLEC4D.

Product Categories/Family for anti-CLEC4D antibody

Antibodies; Abs to Lectins

Applications Tested/Suitable for anti-CLEC4D antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-CLEC4D antibody

Suitable for use in Flow Cytometry.

Other Notes

Small volumes of anti-CLEC4D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLEC4D purchase

MBS609773 is an antibody targeting CLEC4D. Also known as CLEC4D (C-type Lectin Domain Family 4, Member D, C-type Lectin Superfamily Member 8, C-type Lectin-like Receptor 6, CLEC-6, CLECSF8, MCL). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CLEC4D. It may not necessarily be applicable to this product.

NCBI GI #

31542313

NCBI GeneID

338339

NCBI Accession #

NP_525126.2

UniProt Primary Accession #

Q8WXI8

UniProt Secondary Accession #

Q8N5J5

UniProt Related Accession #

Q8WXI8

GenBank Nucleotide #

NM_080387.4

NCBI Official Full Name

C-type lectin domain family 4 member D

NCBI Official Synonym Full Names

C-type lectin domain family 4, member D

NCBI Official Symbol

CLEC4D

NCBI Official Synonym Symbols

MCL; MPCL; CLEC6; CLEC-6; CLECSF8; MGC40078

UniProt Protein Name

C-type lectin domain family 4 member D

UniProt Synonym Protein Names

C-type lectin superfamily member 8; C-type lectin-like receptor 6

Protein Family

C-type lectin domain family

UniProt Gene Name

CLEC4D

UniProt Synonym Gene Names

CLECSF8; MCL

UniProt Entry Name

CLC4D_HUMAN

NCBI Protein Information

C-type lectin domain family 4 member D; OTTHUMP00000239173; OTTHUMP00000239174; C-type lectin receptor; macrophage C-type lectin; C-type lectin-like receptor 6; C-type lectin superfamily member 8; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8

NCBI Summary for CLEC4D

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq]

UniProt Comments for CLEC4D

CLEC4D: Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: integral to membrane

Molecular Function: carbohydrate binding

Biological Process: innate immune response

Research Articles on CLEC4D

1. Cross-linking of the receptor leads to a rapid internalization suggesting that CLECSF8 constitutes and endocytic receptor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CLEC4D antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with CLEC4D and Blood