Mouse Anti-PGLYRP2 Monoclonal Antibody – Cat# MBS609787

PGLYRP2 Antibody – Mouse Monoclonal

Name: PGLYRP2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS609787
Price: 620 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS609787

Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules that recognize bacteria and their unique cell wall component, peptidoglycan (PGN). Mammals have four PGRPs, designated in humans PGRP-S (24kD), PGRPL (60-65kD), PGRP-I alpha (38kD),… More details

$620 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PGRP-L (PGLYRP2), Monoclonal Antibody

Full Product Name

PGRP-L (N-acetylmuramoyl-L-alanine Amidase, Peptidoglycan Recognition Protein 2, Peptidoglycan Recognition Protein Long, PGLYRP2, PGLYRPL, PGRPL, UNQ3103/PRO10102)

Product Gene Name

anti-PGLYRP2 antibody

Product Synonym Names

Anti -PGRP-L (N-acetylmuramoyl-L-alanine Amidase, Peptidoglycan Recognition Protein 2, Peptidoglycan Recognition Protein Long, PGLYRP2, PGLYRPL, PGRPL, UNQ3103/PRO10102)

Clonality

Monoclonal

Isotype

IgG1, k

Clone Number

10K303

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 50% glycerol.

Purity/Purification

Ascites
Ascites

Specificity

Recognizes human PGRP-L.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

62,217 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (15579456..15590315, complement). Location: 19p13.12

OMIM

608199

3D Structure

ModBase 3D Structure for Q96PD5

Immunogen

Peptidoglycan recognition protein (PGRP)-L purified from human protein.

Positive Control

Human plasma

Product Categories/Family for anti-PGLYRP2 antibody

Antibodies; Abs to Receptors

Applications Tested/Suitable for anti-PGLYRP2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-PGLYRP2 antibody

Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:2,000

Other Notes

Small volumes of anti-PGLYRP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGLYRP2 purchase

MBS609787 is an antibody targeting PGLYRP2. Also known as PGRP-L (N-acetylmuramoyl-L-alanine Amidase, Peptidoglycan Recognition Protein 2, Peptidoglycan Recognition Protein Long, PGLYRP2, PGLYRPL, PGRPL, UNQ3103/PRO10102). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PGLYRP2. It may not necessarily be applicable to this product.

NCBI GI #

219518193

NCBI GeneID

114770

NCBI Accession #

AAI44239.1

UniProt Primary Accession #

Q96PD5

UniProt Secondary Accession #

Q68CK1; Q96N74; Q9UC60; A8K8C7; B2RMZ2

UniProt Related Accession #

Q96PD5

NCBI Official Full Name

Peptidoglycan recognition protein 2

NCBI Official Synonym Full Names

peptidoglycan recognition protein 2

NCBI Official Symbol

PGLYRP2

NCBI Official Synonym Symbols

tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha

UniProt Protein Name

N-acetylmuramoyl-L-alanine amidase

UniProt Synonym Protein Names

Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long

UniProt Gene Name

PGLYRP2

UniProt Synonym Gene Names

PGLYRPL; PGRPL; PGRP-L

UniProt Entry Name

PGRP2_HUMAN

NCBI Protein Information

N-acetylmuramoyl-L-alanine amidase; peptidoglycan recognition protein L; peptidoglycan recognition protein long

NCBI Summary for PGLYRP2

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]

UniProt Comments for PGLYRP2

PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.5.1.28; Secreted, signal peptide; Secreted; Receptor, misc.

Chromosomal Location of Human Ortholog: 19p13.12

Cellular Component: membrane; intracellular

Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity

Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; peptide amidation; detection of bacterium; negative regulation of interferon-gamma production; regulation of inflammatory response; innate immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process

Research Articles on PGLYRP2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PGLYRP2 antibody

Reference Product	PubMed Publications
NOD2 antibody	>4 publications with PGLYRP2 and NOD2
JUN antibody	>4 publications with PGLYRP2 and JUN

Diseases associated with anti-PGLYRP2 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>6 publications with PGLYRP2 and Inflammation
Neoplasms Antibodies	>2 publications with PGLYRP2 and Neoplasms
Edema Antibodies	>1 publications with PGLYRP2 and Edema
Immune System Diseases Antibodies	>1 publications with PGLYRP2 and Immune System Diseases
Hyperplasia Antibodies	>1 publications with PGLYRP2 and Hyperplasia
Liver Diseases Antibodies	>1 publications with PGLYRP2 and Liver Diseases

Organs/Tissues associated with anti-PGLYRP2 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>6 publications with PGLYRP2 and Liver