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C-646, HAT Inhibitor (4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6104306

Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM). Induces apoptosis in prostate cancer cells. Enhances fear extinction memory and synaptic plasticity in mice. Promotes tau deacetylation reducing levels of pathogenic p-tau.… More details

$455 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-646, HAT Inhibitor, Biochemical
Full Product Name
C-646, HAT Inhibitor (4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid)
Host
Synthetic
Form/Format
Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
Purity/Purification
Highly Purified
~98% (TLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
445.4
CAS Number
328968-36-1
Molecular Formula
C24H19N3O6
Solubility
DMSO (~10mg/ml)

Testing Data of C-646, HAT Inhibitor biochemical

C-646, HAT Inhibitor (4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid)
C-646, HAT Inhibitor (4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid) Biochemical – Cat# MBS6104306

Other Notes

Small volumes of C-646, HAT Inhibitor biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C-646, HAT Inhibitor purchase

MBS6104306 is a biochemical targeting C-646, HAT Inhibitor. Also known as C-646, HAT Inhibitor (4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid). Host: Synthetic.
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