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RepSox (2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine, E-616452)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6105756

Cell-permeable. A TGF-b type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC =4nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse fibroblasts through… More details

$245 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RepSox, Biochemical
Full Product Name
RepSox (2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine, E-616452)
Form/Format
Supplied as an off-white solid.
Purity/Purification
Highly Purified
~98% (HPLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~287.32
CAS Number
446859-33-2
Molecular Formula
C??H??N?
Solubility
DMSO (>20mg/ml)

Product Categories/Family for RepSox biochemical

Biochemicals; Biochem-Inhibitors

Other Notes

Small volumes of RepSox biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RepSox purchase

MBS6105756 is a biochemical targeting RepSox. Also known as RepSox (2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine, E-616452).
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