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A77 1726 (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6109892

The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function More details

$510 / 250 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
A77 1726, Biochemical
Full Product Name
A77 1726 (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M)
Purity/Purification
~90%
Preparation and Storage
May be stored at RT for short-term only. Long-term storage is recommended at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
270.21
CAS Number
163451-81-8
Molecular Formula
C12H9F3N2O2
Atmosphere
Inert gas
Melting Point
222-232ºC
Method for Determining Identity
Proton NMR Spectroscopic Analysis
Solubility
DMSO, Methanol
TLC Conditions
SiO2: Dichloromethane: Methanol: NH4OH; 8ml: 2ml: 5 drops; Visualized with UV and KMnO4; Single spot; Rf=0.5.

Product Categories/Family for A77 1726 biochemical

Biochemicals; Biochem-Inhibitors

Structure of A77 1726 biochemical

Structure of A0001-67.
A77 1726 (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M) Biochemical – Cat# MBS6109892

Other Notes

Small volumes of A77 1726 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for A77 1726 purchase

MBS6109892 is a biochemical targeting A77 1726. Also known as A77 1726 (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M).
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