Rabbit Anti-sodA Polyclonal Antibody – Cat# MBS611036

WB: L6 cell lysate was probed with MBS611036 (0.5ug/ml).

Superoxide Dismutase, Mn (sodA) Antibody – Rabbit Polyclonal

Name: sodA Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS611036
Price: 1125 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS611036

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Superoxide Dismutase, Mn (sodA), Polyclonal Antibody

Full Product Name

Superoxide Dismutase, Mn (SOD)

Product Gene Name

anti-sodA antibody

Product Synonym Names

Anti -Superoxide Dismutase, Mn (SOD)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Bovine, Human, Mouse, Rat

Form/Format

Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human MnSOD at ~24kD. Does not react with canine. Species Crossreactivity: mouse, rat and bovine

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

23,097 Da

Chromosome Location

NC_000913.2 (4098833..4099453)

3D Structure

ModBase 3D Structure for P00448

Immunogen

Recombinant human MnSOD (manganous superoxide dismutase)

Product Categories/Family for anti-sodA antibody

Antibodies; Abs to Superoxide Dismutase

Applications Tested/Suitable for anti-sodA antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-sodA antibody

Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.5-2ug/ml. Detects MnSOD in RIPA lysates of rat L6 RIPA cells. L6 cell lysates were resolved by electrophoresis and transferred to nitrocellulose probed with S8060-10A. Proteins were visualized using an IgG (HRP) Pab Gt xRb and a chemiluminescence detection system.
Immunohistochemistry(paraffin): 10ug/ml. Detected MnSOD in paraffin embedded rat brain tissue sections.

Other Notes

Small volumes of anti-sodA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for sodA purchase

MBS611036 is an antibody targeting sodA. Also known as Superoxide Dismutase, Mn (SOD). Reactive in Bovine, Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for sodA. It may not necessarily be applicable to this product.

NCBI GI #

49176442

NCBI GeneID

948403

NCBI Accession #

NP_418344.3

UniProt Primary Accession #

P00448

UniProt Secondary Accession #

Q2M8K5

GenBank Nucleotide #

NC_000913.2

NCBI Official Full Name

superoxide dismutase, Mn

NCBI Official Symbol

sodA

NCBI Official Synonym Symbols

ECK3901; JW3879

UniProt Protein Name

Superoxide dismutase [Mn]

UniProt Synonym Protein Names

MnSOD

Protein Family

Superoxide dismutase

UniProt Gene Name

sodA

UniProt Entry Name

SODM_ECOLI

NCBI Protein Information

superoxide dismutase, Mn

NCBI Summary for sodA

SoxRS regulon. [More information is available at EcoGene: EG10953].

UniProt Comments for sodA

Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity: 2 superoxide + 2 H+ = O2 + H2O2.

Cofactor: Binds 1 manganese ion per subunit.

Subunit structure: Homodimer.

Sequence similarities: Belongs to the iron/manganese superoxide dismutase family.

Research Articles on sodA

1. emphasize the role of residue 66 in catalysis and inhibition and provide a structural explanation for differences in catalytic properties between human and certain bacterial forms of manganese superoxide dismutases

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-sodA antibody

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