Rabbit Anti-CYBRD1 Polyclonal Antibody – Cat# MBS611637

Duodenal Cytochrome B (CYBRD1) Antibody – Rabbit Polyclonal

Name: CYBRD1 Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS611637
Price: 905 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS611637

Iron is an essential element for a variety physiological process. A variety of proteins are involved in the transport of iron. Most dietary iron exists in the form of ferric iron complexes which must be reduced to yield ferrous ion before it can be taken up… More details

$905 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Duodenal Cytochrome b (CYBRD1), Polyclonal Antibody

Full Product Name

Duodenal Cytochrome b (Dcytb)

Product Gene Name

anti-CYBRD1 antibody

Product Synonym Names

Anti -Duodenal Cytochrome b (Dcytb)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Supplied as a liquid in PBS, 0.05% sodium azide.

Purity/Purification

Serum
Serum

Specificity

Recognizes mouse Duodenal Cytochrome b (Dcytb). No significant sequene homology exists with b558 or other reductases.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

31,641 Da

OMIM

605745

3D Structure

ModBase 3D Structure for Q53TN4

Immunogen

Synthetic peptide consisting of 20aa sequence located within the cytoplasmic C-terminus of mouse DCYTB (KLH). Species sequence homology: human: 70%.

Product Categories/Family for anti-CYBRD1 antibody

Antibodies; Abs to Enzymes; Cytochrome

Applications Tested/Suitable for anti-CYBRD1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-CYBRD1 antibody

Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000 (ECL).
ELISA: 1:10,000-1:50,000. Control peptide can be used to coat ELISA plates at 1ug/ml.

Other Notes

Small volumes of anti-CYBRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYBRD1 purchase

MBS611637 is an antibody targeting CYBRD1. Also known as Duodenal Cytochrome b (Dcytb). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CYBRD1. It may not necessarily be applicable to this product.

NCBI GI #

47522364

UniProt Primary Accession #

Q53TN4

UniProt Secondary Accession #

Q6KC16; Q6KC17; Q6P147; Q9H0Q8; Q9H5G5; B2RE79

NCBI Official Full Name

duodenal cytochrome b

UniProt Protein Name

Cytochrome b reductase 1

UniProt Synonym Protein Names

Duodenal cytochrome b; Ferric-chelate reductase 3

Protein Family

Cytochrome b reductase

UniProt Gene Name

CYBRD1

UniProt Synonym Gene Names

DCYTB; FRRS3

UniProt Entry Name

CYBR1_HUMAN

NCBI Summary for CYBRD1

This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]

UniProt Comments for CYBRD1

CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, iron; EC 1.-.-.-; Motility/polarity/chemotaxis; Transporter; Transporter, ion channel; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: brush border membrane; integral to membrane; plasma membrane

Molecular Function: oxidoreductase activity, oxidizing metal ions; metal ion binding; ferric-chelate reductase activity

Biological Process: cellular iron ion homeostasis; transmembrane transport; response to iron ion

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CYBRD1 antibody

Reference Product	PubMed Publications
FLNA antibody	>12 publications with CYBRD1 and FLNA

Pathways associated with anti-CYBRD1 antibody

Products by Pathway	Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram

Diseases associated with anti-CYBRD1 antibody

Disease Name	Pubmed Publications
Genetic Diseases, Inborn Antibodies	>6 publications with CYBRD1 and Genetic Diseases, Inborn
Carcinoma Antibodies	>4 publications with CYBRD1 and Carcinoma
Anemia Antibodies	>4 publications with CYBRD1 and Anemia
Adenocarcinoma Antibodies	>2 publications with CYBRD1 and Adenocarcinoma
Colorectal Neoplasms Antibodies	>1 publications with CYBRD1 and Colorectal Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with CYBRD1 and Carcinoma, Hepatocellular
Inflammation Antibodies	>1 publications with CYBRD1 and Inflammation
Esophageal Neoplasms Antibodies	>1 publications with CYBRD1 and Esophageal Neoplasms
Drug Toxicity Antibodies	>1 publications with CYBRD1 and Drug Toxicity
Myelodysplastic Syndromes Antibodies	>1 publications with CYBRD1 and Myelodysplastic Syndromes

Organs/Tissues associated with anti-CYBRD1 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>19 publications with CYBRD1 and Intestine
Liver Antibodies	>10 publications with CYBRD1 and Liver
Blood Antibodies	>8 publications with CYBRD1 and Blood
Kidney Antibodies	>3 publications with CYBRD1 and Kidney
Esophagus Antibodies	>1 publications with CYBRD1 and Esophagus
Spleen Antibodies	>1 publications with CYBRD1 and Spleen
Bone Antibodies	>1 publications with CYBRD1 and Bone
Pancreas Antibodies	>1 publications with CYBRD1 and Pancreas
Heart Antibodies	>1 publications with CYBRD1 and Heart
Brain Antibodies	>1 publications with CYBRD1 and Brain