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CD138 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6120800

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CD138, Monoclonal Antibody
Full Product Name
CD138 (Syndecan-1,SDC1,SDC) (AP)
Product Gene Name
anti-CD138 antibody
Product Synonym Gene Name
SDC1
Product Synonym Names
Syndecan-1,SDC1,SDC
Clonality
Monoclonal
Isotype
IgG1
Clone Number
531CT15.4.1;531CT15.1.4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein G Affinity Chromatography
Specificity
Recognizes human CD138.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C with the addition of glycerol. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive.
Molecular Weight
32,462 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (20400558..20425194, complement). Location: 2p24.1
OMIM
186355
3D Structure
ModBase 3D Structure for P18827
Immunogen
Purified His-tagged CD138 protein (fragment).
Conjugate
AP

Product Categories/Family for anti-CD138 antibody

Antibodies; CD Markers
Applications Tested/Suitable for anti-CD138 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CD138 antibody
ELISA: 1:1,000
WB: 1:100
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-CD138 antibody

Western blot analysis of in HepG2 cell line lysates (35ug/lane). This demonstrates the CD138 antibody detected the CD138 protein (arrow).
Mouse Anti-CD138 Monoclonal Antibody – Cat# MBS6120800

Product References and Citations for anti-CD138 antibody

Tsai, E.W., et al. Transplantation 90(8):875-881(2010) Hozumi, K., et al. FEBS Lett. 584(15):3381-3385(2010) Zyada, M.M., et al. Ann Diagn Pathol 14(3):153-161(2010) Al-Shibli, K., et al. APMIS 118(5):371-382(2010) Szumilo, J., et al. Folia Histochem. Cytobiol. 47(4):571-578(2009)

Other Notes

Small volumes of anti-CD138 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD138 purchase

MBS6120800 is an antibody targeting CD138. Also known as CD138 (Syndecan-1,SDC1,SDC) (AP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD138. It may not necessarily be applicable to this product.

NCBI GI #
55749480
NCBI GeneID
6382
NCBI Accession #
NP_001006947.1
UniProt Primary Accession #
P18827
UniProt Secondary Accession #
Q53QV0; Q546D3; Q96HB7; D6W523
UniProt Related Accession #
P18827; AAB21434; AAB23935
GenBank Nucleotide #
NM_001006946.1
NCBI Official Full Name
syndecan-1
NCBI Official Synonym Full Names
syndecan 1
NCBI Official Symbol
SDC1
NCBI Official Synonym Symbols
SDC; CD138; SYND1; syndecan
UniProt Protein Name
Syndecan-1
Protein Family
Syndecan
UniProt Gene Name
SDC1
UniProt Synonym Gene Names
SDC; SYND1
UniProt Entry Name
SDC1_HUMAN
NCBI Protein Information
syndecan-1; CD138 antigen; syndecan proteoglycan 1; heparan sulfate proteoglycan fibroblast growth factor receptor

UniProt Comments for CD138

syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family.

Protein type: Motility/polarity/chemotaxis; Extracellular matrix; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: lysosomal lumen; focal adhesion; cell surface; protein complex; Golgi lumen; integral to plasma membrane; cytoplasm; plasma membrane; external side of plasma membrane

Molecular Function: protein C-terminus binding; protein binding; glycoprotein binding

Biological Process: phototransduction, visible light; extracellular matrix organization and biogenesis; response to cAMP; myoblast development; wound healing; glycosaminoglycan metabolic process; striated muscle cell development; response to toxin; response to glucocorticoid stimulus; pathogenesis; lipoprotein metabolic process; Wnt receptor signaling pathway through beta-catenin; Sertoli cell development; odontogenesis; chondroitin sulfate metabolic process; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; response to hydrogen peroxide; ureteric bud development; carbohydrate metabolic process; inflammatory response; response to calcium ion; retinoid metabolic process
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Research Articles on CD138

1. SDC1 expression was not different in patients with advanced vs no/limited LBD.A significant positive correlation between gene expression & BM plasma protein levels was observed for SDC1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD138 antibody

 Reference Product  PubMed Publications
 FGF2 antibody  >47 publications with CD138 and FGF2
 HGF antibody  >8 publications with CD138 and HGF
 CCL5 antibody  >6 publications with CD138 and CCL5
 PTN antibody  >3 publications with CD138 and PTN
 LACRT antibody  >2 publications with CD138 and LACRT
 CASK antibody  >2 publications with CD138 and CASK
 SDCBP antibody  >1 publications with CD138 and SDCBP
 IL8 antibody  >1 publications with CD138 and IL8
 IGFBP7 antibody  >1 publications with CD138 and IGFBP7
 CTSG antibody  >1 publications with CD138 and CTSG

Pathways associated with anti-CD138 antibody

 Products by Pathway  Pathway Diagram
 A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies  A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies  Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
 Chylomicron-mediated Lipid Transport Pathway antibodies  Chylomicron-mediated Lipid Transport Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram

Diseases associated with anti-CD138 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >388 publications with CD138 and Neoplasms
 Cardiovascular Diseases Antibodies  >162 publications with CD138 and Cardiovascular Diseases
 Hematologic Diseases Antibodies  >152 publications with CD138 and Hematologic Diseases
 Inflammation Antibodies  >53 publications with CD138 and Inflammation
 Adenocarcinoma Antibodies  >50 publications with CD138 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >36 publications with CD138 and Neoplasms, Experimental
 Necrosis Antibodies  >29 publications with CD138 and Necrosis
 Nervous System Diseases Antibodies  >22 publications with CD138 and Nervous System Diseases
 Lung Neoplasms Antibodies  >17 publications with CD138 and Lung Neoplasms
 Liver Diseases Antibodies  >15 publications with CD138 and Liver Diseases

Organs/Tissues associated with anti-CD138 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >264 publications with CD138 and Blood
 Bone Antibodies  >140 publications with CD138 and Bone
 Skin Antibodies  >41 publications with CD138 and Skin
 Lymph Node Antibodies  >39 publications with CD138 and Lymph Node
 Liver Antibodies  >33 publications with CD138 and Liver
 Mouth Antibodies  >32 publications with CD138 and Mouth
 Kidney Antibodies  >29 publications with CD138 and Kidney
 Lung Antibodies  >28 publications with CD138 and Lung
 Muscle Antibodies  >21 publications with CD138 and Muscle
 Intestine Antibodies  >20 publications with CD138 and Intestine
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