Rabbit Anti-ASB5 Polyclonal Antibody – Cat# MBS612123

Western Blot analysis: Detecting Asb-11 in 15ugs of human liver cell lysate using MBS612123 (1:1000).

Ankyrin Repeat and Socs Box-Containing Protein Asb-5 (ASB5) Antibody – Rabbit Polyclonal

Name: ASB5 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS612123
Price: 710 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS612123

The ankyrin repeat and SOCS box-containing (Asb) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box(1). SOCS boxes are carboxy-terminal regions… More details

$710 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ankyrin repeat and SOCs box-containing protein Asb-5 (ASB5), Polyclonal Antibody

Full Product Name

Ankyrin repeat and SOCs box-containing protein, mouse Asb-5 (Asb-11)

Product Gene Name

anti-ASB5 antibody

Product Synonym Names

Anti -Ankyrin repeat and SOCs box-containing protein, mouse Asb-5 (Asb-11)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.1mg/ml BSA, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human Ankyrin repeat and SOCs box-containing protein, mouse Asb-5 (Asb-11).

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

36,341 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (177134824..177198722, complement). Location: 4q34.2

OMIM

615050

3D Structure

ModBase 3D Structure for Q8WWX0

Immunogen

Synthetic peptides corresponding to aa40-51 and aa250-265 of human Asb-11.

Positive Control

Human liver whole cell lysate

Product Categories/Family for anti-ASB5 antibody

Antibodies; Abs to SOCS

Applications Tested/Suitable for anti-ASB5 antibody

Western Blot (WB)

Application Notes for anti-ASB5 antibody

Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1:500-1:1000

Other Notes

Small volumes of anti-ASB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASB5 purchase

MBS612123 is an antibody targeting ASB5. Also known as Ankyrin repeat and SOCs box-containing protein, mouse Asb-5 (Asb-11). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASB5. It may not necessarily be applicable to this product.

NCBI GI #

18254476

NCBI GeneID

140458

NCBI Accession #

NP_543150.1

UniProt Primary Accession #

Q8WWX0

UniProt Related Accession #

Q8WWX0

GenBank Nucleotide #

NM_080874.3

NCBI Official Full Name

ankyrin repeat and SOCS box protein 5

NCBI Official Synonym Full Names

ankyrin repeat and SOCS box containing 5

NCBI Official Symbol

ASB5

NCBI Official Synonym Symbols

ASB-5

UniProt Protein Name

Ankyrin repeat and SOCS box protein 5

Protein Family

Ankyrin repeat and SOCS box protein

UniProt Gene Name

ASB5

UniProt Synonym Gene Names

ASB-5

UniProt Entry Name

ASB5_HUMAN

NCBI Protein Information

ankyrin repeat and SOCS box protein 5; SOCS box protein ASB-5; ankyrin repeat and SOCS box-containing 5

NCBI Summary for ASB5

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008]

UniProt Comments for ASB5

ASB5: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis.

Chromosomal Location of Human Ortholog: 4q34.2

Biological Process: protein ubiquitination

Research Articles on ASB5

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ASB5 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies	Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies	Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram

Organs/Tissues associated with anti-ASB5 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>4 publications with ASB5 and Muscle
Lung Antibodies	>1 publications with ASB5 and Lung
Intestine Antibodies	>1 publications with ASB5 and Intestine
Embryonic Tissue Antibodies	>1 publications with ASB5 and Embryonic Tissue
Heart Antibodies	>1 publications with ASB5 and Heart
Uncharacterized Tissue Antibodies	>1 publications with ASB5 and Uncharacterized Tissue