Mouse Anti-METAP1 Monoclonal Antibody – Cat# MBS6121546

METAP1 Antibody western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the METAP1 antibody detected the METAP1 protein (arrow).

METAP1 Antibody – Mouse Monoclonal

Name: METAP1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6121546
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6121546

METAP1 removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

METAP1, Monoclonal Antibody

Full Product Name

METAP1 (Methionine Aminopeptidase 1, MetAP 1, MAP 1, Peptidase M 1, KIAA0094) (Azide free) (HRP)

Product Gene Name

anti-METAP1 antibody

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

248CT14.6.1

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).

Purity/Purification

Purified by Protein G Affinity Chromatography

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

43,215 Da

OMIM

610151

3D Structure

ModBase 3D Structure for P53582

Immunogen

METAP1 Mab is generated from mouse immunized with METAP1 recombinant protein.

Conjugate

HRP

Product Categories/Family for anti-METAP1 antibody

Antibodies; Enzymes; Protease (Proteinase; Peptidase)

Applications Tested/Suitable for anti-METAP1 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-METAP1 antibody

ELISA: 1:1,000
WB: 1:100-250
Applications are based on unconjugated antibody.

Product References and Citations for anti-METAP1 antibody

Xiao, Q., et al. Biochemistry 49(26):5588-5599(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009) Hu, X.V., et al. Biochemistry 46(44):12833-12843(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

Other Notes

Small volumes of anti-METAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for METAP1 purchase

MBS6121546 is an antibody targeting METAP1. Also known as METAP1 (Methionine Aminopeptidase 1, MetAP 1, MAP 1, Peptidase M 1, KIAA0094) (Azide free) (HRP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for METAP1. It may not necessarily be applicable to this product.

NCBI GI #

164420681

NCBI GeneID

23173

NCBI Accession #

NP_055958.2

UniProt Primary Accession #

P53582

UniProt Secondary Accession #

B4E2E6

UniProt Related Accession #

P53582

GenBank Nucleotide #

NM_015143.2

NCBI Official Full Name

methionine aminopeptidase 1

NCBI Official Synonym Full Names

methionyl aminopeptidase 1

NCBI Official Symbol

METAP1

NCBI Official Synonym Symbols

MAP1A; MetAP1A

UniProt Protein Name

Methionine aminopeptidase 1

UniProt Synonym Protein Names

Peptidase M 1

Protein Family

Methionine aminopeptidase

UniProt Gene Name

METAP1

UniProt Entry Name

MAP11_HUMAN

NCBI Protein Information

methionine aminopeptidase 1; MAP 1; metAP 1; peptidase M 1

UniProt Comments for METAP1

METAP1: a peptidase that removes the amino-terminal methionine from nascent proteins.

Protein type: EC 3.4.11.18; Protease

Chromosomal Location of Human Ortholog: 4q23

Cellular Component: cytoplasm; nucleus; cytosol

Molecular Function: metalloexopeptidase activity; metal ion binding; aminopeptidase activity

Biological Process: rhodopsin mediated signaling; regulation of translation; phototransduction, visible light; regulation of rhodopsin mediated signaling; peptidyl-methionine modification; proteolysis; N-terminal protein amino acid modification

Research Articles on METAP1

1. Data indicate that pyridinylpyrimidine-based molecules displayed species specificity behavior against methionine aminopeptidases (MetAPs).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-METAP1 antibody

Reference Product	PubMed Publications
METAP2 antibody	>21 publications with METAP1 and METAP2

Pathways associated with anti-METAP1 antibody

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Associated With Visual Transduction Pathway antibodies	Diseases Associated With Visual Transduction Pathway Diagram
Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway antibodies	Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
The Phototransduction Cascade Pathway antibodies	The Phototransduction Cascade Pathway Diagram
Visual Phototransduction Pathway antibodies	Visual Phototransduction Pathway Diagram

Organs/Tissues associated with anti-METAP1 antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>4 publications with METAP1 and Vascular
Umbilical Cord Antibodies	>1 publications with METAP1 and Umbilical Cord
Embryonic Tissue Antibodies	>1 publications with METAP1 and Embryonic Tissue