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HCG-beta Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6123222

MBS6123222 is an antibody targeting HCG-beta. Also known as HCG-beta (CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB) (AP). Reactive in Human. Host: Mouse. More details

$980 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HCG-beta, Monoclonal Antibody
Full Product Name
HCG-beta (CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB) (AP)
Product Gene Name
Product Synonym Names
CG-beta; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin Subunit beta; hCGB
Clonality
Monoclonal
Isotype
IgG1+IgG1
Clone Number
HCGb/54+ HCGb/459
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A/G Affinity Chromatography.
Specificity
Recognizes human HCG-beta.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
17,739 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (49526126..49527632, complement). Location: 19q13.32
OMIM
118860
3D Structure
ModBase 3D Structure for P01233
Immunogen
Recombinant hCG beta protein. Cellular Localization: Cytoplasmic, secreted
Conjugate
AP
Positive Control
Placenta
Applications Tested/Suitable for anti-HCG-beta antibody
Immunohistochemistry (IHC)
Application Notes for anti-HCG-beta antibody
Applications are based on unconjugated antibody.

Immunohistochemistry (IHC) of anti-HCG-beta antibody

Formalin-fixed, paraffin-embedded human placenta stained using 168787. Note specific membrane staining.
Mouse Anti-HCG-beta Monoclonal Antibody – Cat# MBS6123222

Product References and Citations for anti-HCG-beta antibody

1. Cocquebert M et. al. Am J Physiol Endocrinol Metab. 2012;303(8):E950-8.

Other Notes

Small volumes of anti-HCG-beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HCG-beta. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
choriogonadotropin subunit beta
NCBI Official Synonym Full Names
chorionic gonadotropin, beta polypeptide
NCBI Official Symbol
CGB
NCBI Official Synonym Symbols
CGB3; CGB5; CGB7; CGB8; hCGB
UniProt Protein Name
Choriogonadotropin subunit beta
UniProt Synonym Protein Names
Chorionic gonadotrophin chain beta
UniProt Gene Name
CGB
UniProt Synonym Gene Names
CGB3; CG-beta
UniProt Entry Name
CGHB_HUMAN
NCBI Protein Information
choriogonadotropin subunit beta; CG-beta; chorionic gonadotropin beta chain; chorionic gonadotrophin chain beta; chorionic gonadotropin beta subunit; chorionic gonadotropin beta 3 subunit

NCBI Summary for HCG-beta

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for HCG-beta

CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; apoptosis; peptide hormone processing; female gamete generation; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HCG-beta antibody

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