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Thyrotropin-Releasing Hormone Receptor (TRHR) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS612432

MBS612432 is an antibody targeting TRHR. Also known as Thyrotropin-Releasing Hormone Receptor (TRH-R). Reactive in Human. Host: Rabbit. More details

$865 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Thyrotropin-Releasing Hormone Receptor (TRHR), Polyclonal Antibody
Full Product Name
Thyrotropin-Releasing Hormone Receptor (TRH-R)
Product Gene Name
Product Synonym Names
Anti -Thyrotropin-Releasing Hormone Receptor (TRH-R)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes Human Thyrotropin-Releasing Hormone Receptor (TRH-R) (TRHR). Species Crossreactivity: Human.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
45,085 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (110099676..110131813). Location: 8q23
OMIM
188545
3D Structure
ModBase 3D Structure for P34981
Immunogen
Synthetic peptide, KLH-conjugated. Epitope: C-terminal domain of human

Product Categories/Family for anti-TRHR antibody

Applications Tested/Suitable for anti-TRHR antibody
Immunohistochemistry (IHC)
Application Notes for anti-TRHR antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: Immunohistochemistry: 20ug/ml

Immunohistochemistry (IHC) of anti-TRHR antibody

TRHR (20ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human brain, neuron, followed by biotinylated goat rabbit IgG secondary, alkaline phosphatase-streptavidin and chromogen.
Rabbit Anti-TRHR Polyclonal Antibody – Cat# MBS612432

Other Notes

Small volumes of anti-TRHR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRHR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thyrotropin-releasing hormone receptor
NCBI Official Synonym Full Names
thyrotropin-releasing hormone receptor
NCBI Official Symbol
TRHR
NCBI Official Synonym Symbols
MGC141920
UniProt Protein Name
Thyrotropin-releasing hormone receptor
UniProt Synonym Protein Names
Thyroliberin receptor
UniProt Gene Name
TRHR
UniProt Entry Name
TRFR_HUMAN
NCBI Protein Information
thyrotropin-releasing hormone receptor; TRH-R; OTTHUMP00000227881; thyroliberin receptor

NCBI Summary for TRHR

Thyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.[supplied by OMIM]
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UniProt Comments for TRHR

TRHR: Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 8q23

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: thyrotropin-releasing hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRHR antibody

 Reference Product  PubMed Publications
 TRH antibody  >42 publications with TRHR and TRH

Organs/Tissues associated with anti-TRHR antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >1 publications with TRHR and Mixed
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