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Aquaporin 10 (AQP10) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS612732

Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses… More details

$905 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Aquaporin 10 (AQP10), Polyclonal Antibody
Full Product Name
Aquaporin 10 (AQP10)
Product Gene Name
Product Synonym Names
Anti -Aquaporin 10 (AQP10)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.4, 40% glycerol.
Purity/Purification
Serum
Serum
Specificity
Recognizes human Aquaporin 10. The 17aa peptide is unique to AQP10 without significant homology to any other AQPs.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
31,763 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (154293592..154297801). Location: 1q21.3
OMIM
606578
3D Structure
ModBase 3D Structure for Q96PS8
Immunogen
A 17aa synthetic peptide within the cytoplasmic, C-terminal region of human AQP10 coupled to KLH
Note
We recommend the use of 0.5-1% milk in all primary/secondary antibody-enzyme conjugate incubations in order to suppress non-specific bands.
Optimal dilutions to be determined by the researcher.

Product Categories/Family for anti-AQP10 antibody

Applications Tested/Suitable for anti-AQP10 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-AQP10 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:10,000-1:50,000; Control peptide (A3000-70) can be used to coat ELISA plates at 1ug/ml.
Western Blot: 1:1000-1:5000

Other Notes

Small volumes of anti-AQP10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AQP10 purchase

MBS612732 is an antibody targeting AQP10. Also known as Aquaporin 10 (AQP10). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AQP10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Aquaporin 10
NCBI Official Synonym Full Names
aquaporin 10
NCBI Official Symbol
AQP10
NCBI Official Synonym Symbols
AQPA_HUMAN
UniProt Protein Name
Aquaporin-10
UniProt Synonym Protein Names
Aquaglyceroporin-10; Small intestine aquaporin
Protein Family
UniProt Gene Name
AQP10
UniProt Entry Name
AQP10_HUMAN
NCBI Protein Information
aquaporin-10; AQP-10; OTTHUMP00000034195; OTTHUMP00000034196; aquaglyceroporin-10; small intestine aquaporin

NCBI Summary for AQP10

This gene encodes a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea. [provided by RefSeq]
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UniProt Comments for AQP10

AQP10: Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, aquaporin family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: urea transmembrane transporter activity; water channel activity; glycerol channel activity

Biological Process: glycerol transport; cellular water homeostasis; water transport; response to toxin; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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