Rabbit Anti-FABP2 Polyclonal Antibody – Cat# MBS612931

Fatty Acid Binding Protein, Intestinal (FABP2) Antibody – Rabbit Polyclonal

Name: FABP2 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS612931
Price: 1230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS612931

Intestinal fatty acid binding protein (I-FABP) is specific localized in the small bowel epithelium. I-FABP is detectable in serum and urine after ischemic injury to the small bowel. More details

$1230 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fatty Acid Binding Protein, Intestinal (FABP2), Polyclonal Antibody

Full Product Name

Fatty Acid Binding Protein, Intestinal (FABP)

Product Gene Name

anti-FABP2 antibody

Product Synonym Names

Anti -Fatty Acid Binding Protein, Intestinal (FABP)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Porcine, Rat, Sheep

Form/Format

Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified immunoglobulin

Specificity

Recognizes human intestinal fatty acid binding protein (I-FABP) of both natural and recombinant origin. Specificity was further assessed by ELISA and Western Blot. No crossreactivities with other FABP types have been detected. Species Crossreactivity: rat, mouse, sheep and porcine

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

15,207 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (120238405..120243316, complement). Location: 4q28-q31

OMIM

134640

3D Structure

ModBase 3D Structure for P12104

Immunogen

Purified human intestinal fatty acid binding protein

Product Categories/Family for anti-FABP2 antibody

Antibodies; Abs to Fatty Acid Binding Protein

Applications Tested/Suitable for anti-FABP2 antibody

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-FABP2 antibody

Suitable for use in staining cells containing I-FABP in cells cultured on cover slip (Immunohistochemistry), Western Blot and ELISA.
Dilution: Immunohistochemistry: 1:10
Western Blot: 1:10

Other Notes

Small volumes of anti-FABP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FABP2 purchase

MBS612931 is an antibody targeting FABP2. Also known as Fatty Acid Binding Protein, Intestinal (FABP). Reactive in Human, Mouse, Porcine, Rat, Sheep. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FABP2. It may not necessarily be applicable to this product.

NCBI GI #

194097325

NCBI GeneID

2169

NCBI Accession #

NP_000125.2

UniProt Primary Accession #

P12104

UniProt Secondary Accession #

Q2NKJ1

UniProt Related Accession #

P12104

GenBank Nucleotide #

NM_000134.3

NCBI Official Full Name

fatty acid-binding protein, intestinal

NCBI Official Synonym Full Names

fatty acid binding protein 2, intestinal

NCBI Official Symbol

FABP2

NCBI Official Synonym Symbols

FABPI; I-FABP; MGC133132

UniProt Protein Name

Fatty acid-binding protein, intestinal

UniProt Synonym Protein Names

Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein

Protein Family

Fatty acid-binding protein

UniProt Gene Name

FABP2

UniProt Synonym Gene Names

FABPI

UniProt Entry Name

FABPI_HUMAN

NCBI Protein Information

fatty acid-binding protein, intestinal; OTTHUMP00000163925; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein

NCBI Summary for FABP2

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq]

UniProt Comments for FABP2

FABP2: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Chromosomal Location of Human Ortholog: 4q28-q31

Cellular Component: cytoplasm

Molecular Function: transporter activity; fatty acid binding

Biological Process: transport; digestion

Research Articles on FABP2

1. The finding of ths study was the lack of association of the Thr54/Ala54 and Thr54/Thr54 fatty acid binding protein 2 genotypes with metabolic syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-FABP2 antibody

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PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram
PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram

Diseases associated with anti-FABP2 antibody

Disease Name	Pubmed Publications
Insulin Resistance Antibodies	>63 publications with FABP2 and Insulin Resistance
Obesity Antibodies	>42 publications with FABP2 and Obesity
Dyslipidemias Antibodies	>19 publications with FABP2 and Dyslipidemias
Hyperlipidemias Antibodies	>15 publications with FABP2 and Hyperlipidemias
Intestinal Diseases Antibodies	>14 publications with FABP2 and Intestinal Diseases
Fatty Liver Antibodies	>14 publications with FABP2 and Fatty Liver
Metabolic Syndrome X Antibodies	>11 publications with FABP2 and Metabolic Syndrome X
Arteriosclerosis Antibodies	>8 publications with FABP2 and Arteriosclerosis
Hyperglycemia Antibodies	>7 publications with FABP2 and Hyperglycemia
Kidney Diseases Antibodies	>6 publications with FABP2 and Kidney Diseases

Organs/Tissues associated with anti-FABP2 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>32 publications with FABP2 and Intestine
Connective Tissue Antibodies	>10 publications with FABP2 and Connective Tissue
Kidney Antibodies	>7 publications with FABP2 and Kidney
Mixed Antibodies	>4 publications with FABP2 and Mixed
Placenta Antibodies	>1 publications with FABP2 and Placenta
Brain Antibodies	>1 publications with FABP2 and Brain