Mouse Anti-ATF3 Monoclonal Antibody – Cat# MBS6129711

Activating Transcription Factor 3 (ATF3) Antibody – Mouse Monoclonal

Name: ATF3 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6129711
Price: 995 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6129711

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for… More details

$995 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Activating Transcription Factor 3 (ATF3), Monoclonal Antibody

Full Product Name

Activating Transcription Factor 3 (ATF3, ATF-3, Cyclic AMP-dependent Transcription Factor ATF-3, cAMP-dependent Transcription Factor ATF-3) (AP)

Product Gene Name

anti-ATF3 antibody

Clonality

Monoclonal

Isotype

IgG3,k

Clone Number

6B8

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human Activating Transcription Factor 3.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunogen

Full length recombinant corresponding to aa1-181 from human Activating Transcription Factor 3 (AAH06322) with GST tag. MW of the GST tag alone is 26kD.

Conjugate

Product Categories/Family for anti-ATF3 antibody

Antibodies; Transcription Factors

Applications Tested/Suitable for anti-ATF3 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-ATF3 antibody

Applications are based on unconjugated antibody.

Product References and Citations for anti-ATF3 antibody

1. Steroids and extracellular signal-regulated kinase 1/2 activity suppress activating transcription factor 3 expression in patients with severe asthma. Roussel L, Robins S, Schachter A, Berube J, Hamid Q, Rousseau S.J Allergy Clin Immunol. 2011 Apr 22. 2.Energy restriction-mimetic agents induce apoptosis in prostate cancer cells, in part, through epigenetic activation of KLF6 tumor suppressor gene expression. Chen CH, Huang PH, Chu PC, Chen MC, Chou CC, Wang D, Kulp SK, Teng CM, Wang Q, Chen CS.J Biol Chem. 2011 Feb 3.

Other Notes

Small volumes of anti-ATF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATF3 purchase

MBS6129711 is an antibody targeting ATF3. Also known as Activating Transcription Factor 3 (ATF3, ATF-3, Cyclic AMP-dependent Transcription Factor ATF-3, cAMP-dependent Transcription Factor ATF-3) (AP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ATF3. It may not necessarily be applicable to this product.

NCBI GI #

13623445

NCBI GeneID

467

NCBI Accession #

AAH06322

UniProt Related Accession #

P18847

NCBI Official Full Name

Activating transcription factor 3

NCBI Official Synonym Full Names

activating transcription factor 3

NCBI Official Symbol

ATF3

Protein Family

Activating transcription factor

NCBI Protein Information

cyclic AMP-dependent transcription factor ATF-3

NCBI Summary for ATF3

This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]

Research Articles on ATF3

1. Findings demonstrated ATF3 as an important regulator of epithelial homeostasis by promoting both DNA repair and the death of damaged cells under ZnO NP-induced genotoxic stress.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.