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ARHGAP6 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6130047

ARHGAP6 (Rho GTPase activating protein 6) is similar to the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane of several cellular processes. ARHGAP6 is thought to have two independent functions, one… More details

$995 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARHGAP6, Monoclonal Antibody
Full Product Name
ARHGAP6 (Rho GTPase Activating Protein 6, Rho-type GTPase-activating Protein 6, Rho-type GTPase-activating Protein RhoGAPX-1, RHOGAP6) (AP)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
6B3
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human ARHGAP6.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
300118
3D Structure
ModBase 3D Structure for O43182
Immunogen
Partial recombinant corresponding to aa531-636 from human ARHGAP6 (NP_038286) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
RHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSS
Conjugate
AP

Product Categories/Family for anti-ARHGAP6 antibody

Applications Tested/Suitable for anti-ARHGAP6 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ARHGAP6 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ARHGAP6 antibody

ARHGAP6 monoclonal antibody Western Blot analysis of ARHGAP6 expression in K-562.
Mouse Anti-ARHGAP6 Monoclonal Antibody – Cat# MBS6130047

Testing Data of anti-ARHGAP6 antibody

Detection limit for recombinant GST tagged ARHGAP6 is ~0.3ng/ml as a capture antibody.
Mouse Anti-ARHGAP6 Monoclonal Antibody, Testing Data – Cat# MBS6130047

Product References and Citations for anti-ARHGAP6 antibody

1. Genetic screening in C. Elegans identifies rho- GTPase activating protein 6 as novel HERG regulator. Potet F, Petersen CI, Boutaud O, Shuai W, Stepanovic SZ, Balser JR, Kupershmidt S.J Mol Cell Cardiol. 2009 Feb;46(2):257-67. Epub 2008 Nov 5.

Other Notes

Small volumes of anti-ARHGAP6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARHGAP6 purchase

MBS6130047 is an antibody targeting ARHGAP6. Also known as ARHGAP6 (Rho GTPase Activating Protein 6, Rho-type GTPase-activating Protein 6, Rho-type GTPase-activating Protein RhoGAPX-1, RHOGAP6) (AP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rho GTPase-activating protein 6 isoform 1
NCBI Official Synonym Full Names
Rho GTPase activating protein 6
NCBI Official Symbol
ARHGAP6
NCBI Official Synonym Symbols
RHOGAP6; RHOGAPX-1
UniProt Protein Name
Rho GTPase-activating protein 6
UniProt Synonym Protein Names
Rho-type GTPase-activating protein 6; Rho-type GTPase-activating protein RhoGAPX-1
UniProt Gene Name
ARHGAP6
UniProt Synonym Gene Names
RHOGAP6
UniProt Entry Name
RHG06_HUMAN
NCBI Protein Information
rho GTPase-activating protein 6

NCBI Summary for ARHGAP6

This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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