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Receptor 1 (NMU) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS613185

MBS613185 is an antibody targeting NMU. Also known as NMU Receptor 1 (NMUR1). Reactive in Rat. Host: Rabbit. More details

$905 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NMU Receptor 1, Polyclonal Antibody
Full Product Name
NMU Receptor 1 (NMUR1)
Product Gene Name
Product Synonym Names
Anti -NMU Receptor 1 (NMUR1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide, before the addition of glycerol to 40%.
Purity/Purification
Serum
Serum
Specificity
Recognizes rat NMU Receptor 1 (NMUR1). Species sequence homology: mouse and human, 65%. No significant sequence homology exist with other NMUR2 or Ghrelin receptors.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
19,741 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (56461396..56502465, complement). Location: 4q12
OMIM
605103
3D Structure
ModBase 3D Structure for P48645
Immunogen
A 20 amino acid peptide within the N-terminal extracellular domain, of rat NMUR1. Conjugated to KLH.

Product Categories/Family for anti-NMU antibody

Applications Tested/Suitable for anti-NMU antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-NMU antibody
Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:100,000. Using 50-100ng control peptide/well.

Other Notes

Small volumes of anti-NMU antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NMU. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuromedin-U
NCBI Official Synonym Full Names
neuromedin U
NCBI Official Symbol
NMU
UniProt Protein Name
Neuromedin-U
Protein Family
UniProt Gene Name
NMU
UniProt Synonym Gene Names
NmU-25
UniProt Entry Name
NMU_HUMAN
NCBI Protein Information
neuromedin-U; prepro-NMU

NCBI Summary for NMU

This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015]
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UniProt Comments for NMU

NMU: Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder. Belongs to the NmU family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q12

Cellular Component: extracellular region; terminal button

Molecular Function: neuromedin U receptor binding; receptor binding

Biological Process: regulation of smooth muscle contraction; gastric acid secretion; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; eating behavior; photoperiodism; digestion; positive regulation of hormone secretion; positive regulation of smooth muscle contraction; sensory perception of pain; signal transduction; positive regulation of synaptic transmission
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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