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Splicing Factor, Arginine/Serine-Rich 4 (SRSF4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS613235

MBS613235 is an antibody targeting SRSF4. Also known as Splicing Factor, Arginine/Serine-Rich 4 (SFRS4, Pre-mRNA Splicing Factor SRP75, SRP001LB). Reactive in Human. Host: Rabbit. More details

$365 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Splicing Factor, Arginine/Serine-Rich 4 (SRSF4), Polyclonal Antibody
Full Product Name
Splicing Factor, Arginine/Serine-Rich 4 (SFRS4, Pre-mRNA Splicing Factor SRP75, SRP001LB)
Product Gene Name
Product Synonym Names
Anti -Splicing Factor, Arginine/Serine-Rich 4 (SFRS4, Pre-mRNA Splicing Factor SRP75, SRP001LB)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, sodium azide, 40% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SRFS4.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
56,678 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (29474250..29508637, complement). Location: 1p35.3
OMIM
601940
3D Structure
ModBase 3D Structure for Q08170
Immunogen
Synthetic peptide aa287-301, KSRSPSRHKSKSKSR corresponding to human SFRS4 (KLH). MW: ~56.67kD
Applications Tested/Suitable for anti-SRSF4 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-SRSF4 antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA (serum titer): 1:37,500
Western Blot: Preliminary results: Human lymph node 50, 65kD

Other Notes

Small volumes of anti-SRSF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SRSF4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/arginine-rich splicing factor 4
NCBI Official Synonym Full Names
serine/arginine-rich splicing factor 4
NCBI Official Symbol
SRSF4
NCBI Official Synonym Symbols
SFRS4; SRP75
UniProt Protein Name
Serine/arginine-rich splicing factor 4
UniProt Synonym Protein Names
Pre-mRNA-splicing factor SRP75; SRP001LB; Splicing factor, arginine/serine-rich 4
UniProt Gene Name
SRSF4
UniProt Synonym Gene Names
SFRS4; SRP75
UniProt Entry Name
SRSF4_HUMAN
NCBI Protein Information
serine/arginine-rich splicing factor 4; SRP001LB; OTTHUMP00000003790; SR splicing factor 4; pre-mRNA-splicing factor SRP75; splicing factor, arginine/serine-rich 4

NCBI Summary for SRSF4

This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq]

UniProt Comments for SRSF4

SFRS4: Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family.

Protein type: Spliceosome; RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: nucleoplasm; nuclear speck; nucleus

Molecular Function: nucleotide binding

Biological Process: RNA splicing, via transesterification reactions; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA export from nucleus; negative regulation of nuclear mRNA splicing, via spliceosome; RNA splicing; hemopoietic progenitor cell differentiation; gene expression; mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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