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TGM2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6134187

MBS6134187 is an antibody targeting TGM2. Also known as TGM2 (Transglutaminase-2, TGase-2, TG2, Protein-glutamine gamma-glutamyltransferase 2, Tissue Transglutaminase, Transglutaminase C, TGase C, TG(C), TGC, Transglutaminase H, TGase H, GNAH, G-ALPHA-h)… More details

$995 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TGM2, Monoclonal Antibody
Full Product Name
TGM2 (Transglutaminase-2, TGase-2, TG2, Protein-glutamine gamma-glutamyltransferase 2, Tissue Transglutaminase, Transglutaminase C, TGase C, TG(C), TGC, Transglutaminase H, TGase H, GNAH, G-ALPHA-h) (AP)
Product Gene Name
Product Synonym Names
EC=2.3.2.13
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2F4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human TGM2.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
38,671 Da
Immunogen
Partial recombinant corresponding to aa1-120 from human TGM2 (AAH03551) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE
Conjugate
AP

Product Categories/Family for anti-TGM2 antibody

Applications Tested/Suitable for anti-TGM2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-TGM2 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-TGM2 antibody

Western Blot analysis of TGM2 expression in transfected 293T cell line by TGM2 monoclonal antibody Lane 1: TGM2 transfected lysate (61.7kD). Lane 2: Non-transfected lysate.
Mouse Anti-TGM2 Monoclonal Antibody – Cat# MBS6134187

Immunohistochemistry (IHC) of anti-TGM2 antibody

Immunoperoxidase of monoclonal antibody to TGM2 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3ug/ml]
Mouse Anti-TGM2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6134187

Immunofluorescence (IF) of anti-TGM2 antibody

Immunofluorescence of monoclonal antibody to TGM2 on HeLa cell. [antibody concentration 10ug/ml]
Mouse Anti-TGM2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6134187

Testing Data of anti-TGM2 antibody

Detection limit for recombinant GST tagged TGM2 is ~0.03ng/ml as a capture antibody.
Mouse Anti-TGM2 Monoclonal Antibody, Testing Data – Cat# MBS6134187

Other Notes

Small volumes of anti-TGM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TGM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), mRNA
NCBI Official Synonym Full Names
transglutaminase 2
NCBI Official Symbol
TGM2
NCBI Official Synonym Symbols
TGC; TG(C)
NCBI Protein Information
protein-glutamine gamma-glutamyltransferase 2

NCBI Summary for TGM2

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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