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UPB1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6134474

MBS6134474 is an antibody targeting UPB1. Also known as UPB1 (Beta-ureidopropionase, BUP1, BUP-1, Beta-alanine Synthase, N-carbamoyl-beta-alanine Amidohydrolase) (AP). Reactive in Human. Host: Mouse. More details

$995 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UPB1, Monoclonal Antibody
Full Product Name
UPB1 (Beta-ureidopropionase, BUP1, BUP-1, Beta-alanine Synthase, N-carbamoyl-beta-alanine Amidohydrolase) (AP)
Product Gene Name
Product Synonym Names
EC=3.5.1.6
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3F12
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human UPB1.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
42kDa
OMIM
AF163312 mRNA
3D Structure
ModBase 3D Structure for Q9UBR1
Immunogen
Partial recombinant corresponding to aa285-385 from human UPB1 (NP_057411) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
AINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
Conjugate
AP

Product Categories/Family for anti-UPB1 antibody

Applications Tested/Suitable for anti-UPB1 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-UPB1 antibody
IHC-P: 3ug/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-UPB1 antibody

Western Blot detection against Immunogen (37.11kD).
Mouse Anti-UPB1 Monoclonal Antibody – Cat# MBS6134474

Western Blot (WB) of anti-UPB1 antibody

UPB1 monoclonal antibody. Western Blot analysis of UPB1 expression in human liver.
Mouse Anti-UPB1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6134474

Western Blot (WB) of anti-UPB1 antibody

UPB1 monoclonal antibody. Western Blot analysis of UPB1 expression in Jurkat.
Mouse Anti-UPB1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6134474

Western Blot (WB) of anti-UPB1 antibody

Western Blot analysis of UPB1 expression in transfected 293T cell line by UPB1 monoclonal antibody. Lane 1: UPB1 transfected lysate (43.2kD). Lane 2: Non-transfected lysate.
Mouse Anti-UPB1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6134474

Immunohistochemistry (IHC) of anti-UPB1 antibody

Immunoperoxidase of monoclonal antibody to UPB1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3ug/ml].
Mouse Anti-UPB1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6134474

Testing Data of anti-UPB1 antibody

Detection limit for recombinant GST tagged UPB1 is 1ng/ml as a capture antibody.
Mouse Anti-UPB1 Monoclonal Antibody, Testing Data – Cat# MBS6134474

Other Notes

Small volumes of anti-UPB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UPB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
beta-ureidopropionase
NCBI Official Synonym Full Names
beta-ureidopropionase 1
NCBI Official Symbol
UPB1
NCBI Official Synonym Symbols
BUP1
UniProt Protein Name
Beta-ureidopropionase
UniProt Synonym Protein Names
BUP-1; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolase
Protein Family
UniProt Gene Name
UPB1
UniProt Synonym Gene Names
BUP1
NCBI Protein Information
beta-ureidopropionase

NCBI Summary for UPB1

This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]
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UniProt Comments for UPB1

Converts N-carbamoyl-beta-aminoisobutyrate and N-carbamoyl-beta-alanine (3-ureidopropanoate) to, respectively, beta-aminoisobutyrate and beta-alanine, ammonia and carbon dioxide.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UPB1 antibody

Organs/Tissues associated with anti-UPB1 antibody

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