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ADRA1A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6135204

This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate… More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ADRA1A, Monoclonal Antibody
Full Product Name
ADRA1A (Alpha-1A Adrenergic Receptor, Alpha-1A Adrenoreceptor, Alpha-1A Adrenoceptor, Alpha-1C Adrenergic Receptor, Alpha-adrenergic Receptor 1c, ADRA1C) APC
Product Gene Name
Product Synonym Names
ADRA1A
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
4C7
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human ADRA1A.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
40,638 Da
Immunogen
Partial recombinant corresponding to aa1-27 from human ADRA1A (NP_150646) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MVFLSGNASDSSNCTQPPAPVNISKAI
Conjugate
APC

Product Categories/Family for anti-ADRA1A antibody

Applications Tested/Suitable for anti-ADRA1A antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ADRA1A antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ADRA1A antibody

Western Blot detection against Immunogen (28.71kD).
Mouse Anti-ADRA1A Monoclonal Antibody – Cat# MBS6135204

Western Blot (WB) of anti-ADRA1A antibody

ADRA1A monoclonal antibody Western Blot analysis of ADRA1A expression in HL-60.
Mouse Anti-ADRA1A Monoclonal Antibody, Western Blot (WB) – Cat# MBS6135204

Testing Data of anti-ADRA1A antibody

Detection limit for recombinant GST tagged ADRA1A is ~0.3ng/ml as a capture antibody.
Mouse Anti-ADRA1A Monoclonal Antibody, Testing Data – Cat# MBS6135204

Other Notes

Small volumes of anti-ADRA1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADRA1A purchase

MBS6135204 is an antibody targeting ADRA1A. Also known as ADRA1A (Alpha-1A Adrenergic Receptor, Alpha-1A Adrenoreceptor, Alpha-1A Adrenoceptor, Alpha-1C Adrenergic Receptor, Alpha-adrenergic Receptor 1c, ADRA1C) APC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ADRA1A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
alpha-1A adrenergic receptor isoform 2
NCBI Official Synonym Full Names
adrenoceptor alpha 1A
NCBI Official Symbol
ADRA1A
NCBI Official Synonym Symbols
ADRA1C; ADRA1L1; ALPHA1AAR
NCBI Protein Information
alpha-1A adrenergic receptor

NCBI Summary for ADRA1A

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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