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ASB11 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6135389

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASB11, Monoclonal Antibody
Full Product Name
ASB11 (Ankyrin Repeat and SOCS Box Protein 11, ASB-11, DKFZp779E2460, MGC119168, MGC119169) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
4D11
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human ASB11.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
300626
3D Structure
ModBase 3D Structure for Q8WXH4
Immunogen
Partial recombinant protein corresponding to aa214-324 from human ASB11 (NP_543149) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
KLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLLREGPPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ
Conjugate
APC

Product Categories/Family for anti-ASB11 antibody

Applications Tested/Suitable for anti-ASB11 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ASB11 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ASB11 antibody

Western Blot detection against Immunogen (38.21kD).
Mouse Anti-ASB11 Monoclonal Antibody – Cat# MBS6135389

Testing Data of anti-ASB11 antibody

Detection limit for recombinant GST tagged ASB11 is ~1ng/ml as a capture antibody.
Mouse Anti-ASB11 Monoclonal Antibody, Testing Data – Cat# MBS6135389

Other Notes

Small volumes of anti-ASB11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASB11 purchase

MBS6135389 is an antibody targeting ASB11. Also known as ASB11 (Ankyrin Repeat and SOCS Box Protein 11, ASB-11, DKFZp779E2460, MGC119168, MGC119169) APC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ASB11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ankyrin repeat and SOCS box protein 11 isoform a
NCBI Official Synonym Full Names
ankyrin repeat and SOCS box containing 11
NCBI Official Symbol
ASB11
UniProt Protein Name
Ankyrin repeat and SOCS box protein 11
UniProt Gene Name
ASB11
UniProt Synonym Gene Names
ASB-11
UniProt Entry Name
ASB11_HUMAN
NCBI Protein Information
ankyrin repeat and SOCS box protein 11

NCBI Summary for ASB11

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
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UniProt Comments for ASB11

Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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