• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ATF2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6135412

MBS6135412 is an antibody targeting ATF2. Also known as ATF2 (Cyclic AMP-dependent Transcription Factor ATF-2, cAMP-dependent Transcription Factor ATF-2, Activating Transcription Factor 2, cAMP Response Element-binding Protein CRE-BP1, HB16, Cyclic… More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ATF2, Monoclonal Antibody
Full Product Name
ATF2 (Cyclic AMP-dependent Transcription Factor ATF-2, cAMP-dependent Transcription Factor ATF-2, Activating Transcription Factor 2, cAMP Response Element-binding Protein CRE-BP1, HB16, Cyclic AMP-responsive Element-binding Protein 2, cAMP-responsive Elem
Product Gene Name
anti-ATF2 antibody
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1E12
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human ATF2.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
15,409 Da
Immunogen
Full length recombinant corresponding to aa1-200 from human ATF2 (AAH26175) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARNDSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIV
Conjugate
APC

Product Categories/Family for anti-ATF2 antibody

Antibodies; Transcription Factors
Applications Tested/Suitable for anti-ATF2 antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-ATF2 antibody
IF: 10ug/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ATF2 antibody

Western Blot detection against Immunogen (48.73kD).
Mouse Anti-ATF2 Monoclonal Antibody – Cat# MBS6135412

Immunohistochemistry (IHC) of anti-ATF2 antibody

Immunoperoxidase of monoclonal antibody to ATF2 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3ug/ml].
Mouse Anti-ATF2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6135412

Immunofluorescence (IF) of anti-ATF2 antibody

Immunofluorescence of monoclonal antibody to ATF2 on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-ATF2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6135412

Testing Data of anti-ATF2 antibody

Detection limit for recombinant GST tagged ATF2 is ~3ng/ml as a capture antibody.
Mouse Anti-ATF2 Monoclonal Antibody, Testing Data – Cat# MBS6135412

Other Notes

Small volumes of anti-ATF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ATF2. It may not necessarily be applicable to this product.

NCBI GI #
20072896
NCBI GeneID
1386
NCBI Accession #
BC026175
NCBI Related Accession #
AAH26175
UniProt Secondary Accession #
Q13000; Q3B7B7; Q4ZFU9; Q53RY2; Q8TAR1; A1L3Z2; A4D7U4; A4D7U5; A4D7V1; D3DPE9; G8JLM5
UniProt Related Accession #
P15336
NCBI Official Full Name
Homo sapiens activating transcription factor 2, mRNA
NCBI Official Synonym Full Names
activating transcription factor 2
NCBI Official Symbol
ATF2
NCBI Official Synonym Symbols
HB16; CREB2; TREB7; CREB-2; CRE-BP1
Protein Family
Alcohol O-acetyltransferase
NCBI Protein Information
cyclic AMP-dependent transcription factor ATF-2

NCBI Summary for ATF2

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
Show more

Research Articles on ATF2

1. CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ATF2 antibody

 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of The AP-1 Family Of Transcription Factors Pathway antibodies  Activation Of The AP-1 Family Of Transcription Factors Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram

Diseases associated with anti-ATF2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >143 publications with ATF2 and Neoplasms
 Necrosis Antibodies  >64 publications with ATF2 and Necrosis
 Skin Diseases Antibodies  >37 publications with ATF2 and Skin Diseases
 Inflammation Antibodies  >37 publications with ATF2 and Inflammation
 Nervous System Diseases Antibodies  >32 publications with ATF2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >28 publications with ATF2 and Disease Models, Animal
 Brain Diseases Antibodies  >25 publications with ATF2 and Brain Diseases
 Breast Neoplasms Antibodies  >25 publications with ATF2 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >24 publications with ATF2 and Cardiovascular Diseases
 Drug Toxicity Antibodies  >16 publications with ATF2 and Drug Toxicity

Organs/Tissues associated with anti-ATF2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >75 publications with ATF2 and Blood
 Brain Antibodies  >71 publications with ATF2 and Brain
 Muscle Antibodies  >46 publications with ATF2 and Muscle
 Nerve Antibodies  >35 publications with ATF2 and Nerve
 Vascular Antibodies  >32 publications with ATF2 and Vascular
 Lung Antibodies  >32 publications with ATF2 and Lung
 Bone Antibodies  >30 publications with ATF2 and Bone
 Kidney Antibodies  >27 publications with ATF2 and Kidney
 Liver Antibodies  >27 publications with ATF2 and Liver
 Skin Antibodies  >25 publications with ATF2 and Skin
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000