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NHE3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS613580

Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in… More details

$965 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NHE3, Polyclonal Antibody
Full Product Name
NHE3 (Na, H Exchanger 3)
Product Gene Name
anti-Nhe3 antibody
Product Synonym Names
Anti -NHE3 (Na, H Exchanger 3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as a liquid in 100mM Tris, pH 7.5, 0.2% BSA, 0.05% sodium azide, 40% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes rat NHE3. No significant sequence homology exist with other NHE isoforms (NHE1, 2, 4 and 5). Species Sequence Homology
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Chromosome Location
Chromosome: 2L; NT_033779.4 (6677835..6684357, complement). Location: 26F7-26F7
Immunogen
Synthetic peptide consisting of 22aa within the cytoplasmic, C-terminal domain of rat NHE3.

Product Categories/Family for anti-Nhe3 antibody

Antibodies; Abs to Ion Channel
Applications Tested/Suitable for anti-Nhe3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-Nhe3 antibody
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1-10ug/ml using ECL; A band of ~90kD has been detected in brush border membrane (2).
ELISA: 1:100,000 using 50-100ng control peptide/well.

Other Notes

Small volumes of anti-Nhe3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nhe3 purchase

MBS613580 is an antibody targeting Nhe3. Also known as NHE3 (Na, H Exchanger 3). Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Nhe3. It may not necessarily be applicable to this product.

NCBI GI #
281364513
NCBI GeneID
33939
NCBI Accession #
NP_001097105.3
GenBank Nucleotide #
NM_001103635.2
NCBI Official Full Name
Na[+]/H[+] hydrogen exchanger 3, isoform H
NCBI Official Synonym Full Names
Na[+]/H[+] hydrogen exchanger 3
NCBI Official Symbol
Nhe3
NCBI Official Synonym Symbols
CG11328; DmelCG11328; DmNHE3; nhe3; NHE3
Protein Family
Na(+)/H(+) exchange regulatory cofactor
NCBI Protein Information
CG11328 gene product from transcript CG11328-RH; Na[+]/H[+] hydrogen exchanger 3, isoform H; CG11328-PH; Nhe3-PH; Na[+]/H[+] hydrogen exchanger 3, isoform G; CG11328-PG; Nhe3-PG; Na[+]/H[+] hydrogen exchanger 3, isoform E; CG11328-PE; Nhe3-PE; Na[+]/H[+] hydrogen exchanger 3, isoform D; CG11328-PD; Nhe3-PD

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Nhe3 antibody

 Products by Pathway  Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Sodium/Proton Exchangers Pathway antibodies  Sodium/Proton Exchangers Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram

Organs/Tissues associated with anti-Nhe3 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Nhe3 and Bone
 Connective Tissue Antibodies  >4 publications with Nhe3 and Connective Tissue
 Heart Antibodies  >3 publications with Nhe3 and Heart
 Muscle Antibodies  >3 publications with Nhe3 and Muscle
 Brain Antibodies  >3 publications with Nhe3 and Brain
 Vascular Antibodies  >2 publications with Nhe3 and Vascular
 Embryonic Tissue Antibodies  >2 publications with Nhe3 and Embryonic Tissue
 Ear Antibodies  >1 publications with Nhe3 and Ear
 Kidney Antibodies  >1 publications with Nhe3 and Kidney
 Umbilical Cord Antibodies  >1 publications with Nhe3 and Umbilical Cord
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