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ENDOGL1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6136426

MBS6136426 is an antibody targeting ENDOGL1. Also known as ENDOGL1 (Nuclease EXOG, Mitochondrial, Endonuclease G-like 1, Endo G-like 1, EXOG, ENGL, ENDOGL2) APC. Reactive in Human, Mouse, Rat. Host: Mouse. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ENDOGL1, Monoclonal Antibody
Full Product Name
ENDOGL1 (Nuclease EXOG, Mitochondrial, Endonuclease G-like 1, Endo G-like 1, EXOG, ENGL, ENDOGL2) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2F7
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human ENDOGL1. Species Crossreactivity: mouse and rat.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
604051
3D Structure
ModBase 3D Structure for Q9Y2C4
Immunogen
Partial recombinant protein corresponding to aa269-368, from ENDOGL1 (NP_005098) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
LQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS
Conjugate
APC

Product Categories/Family for anti-ENDOGL1 antibody

Applications Tested/Suitable for anti-ENDOGL1 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-ENDOGL1 antibody
IHC-P: 3ug/ml
IF: 10ug/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ENDOGL1 antibody

ENDOGL1 monoclonal antibody Western Blot analysis of ENDOGL1 expression in HepG2.
Mouse Anti-ENDOGL1 Monoclonal Antibody – Cat# MBS6136426

Western Blot (WB) of anti-ENDOGL1 antibody

ENDOGL1 monoclonal antibody Western Blot analysis of ENDOGL1 expression in Raw 264.7.
Mouse Anti-ENDOGL1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6136426

Western Blot (WB) of anti-ENDOGL1 antibody

ENDOGL1 monoclonal antibody Western Blot analysis of ENDOGL1 expression in NIH/3T3.
Mouse Anti-ENDOGL1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6136426

Immunohistochemistry (IHC) of anti-ENDOGL1 antibody

Immunoperoxidase of monoclonal antibody to EXOG on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3ug/ml].
Mouse Anti-ENDOGL1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6136426

Immunofluorescence (IF) of anti-ENDOGL1 antibody

Immunofluorescence of monoclonal antibody to EXOG on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-ENDOGL1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6136426

Other Notes

Small volumes of anti-ENDOGL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ENDOGL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclease EXOG, mitochondrial isoform 1
UniProt Protein Name
Nuclease EXOG, mitochondrial
UniProt Synonym Protein Names
Endonuclease G-like 1
UniProt Gene Name
EXOG
UniProt Synonym Gene Names
ENDOGL1; ENDOGL2; ENGL; Endo G-like 1
UniProt Entry Name
EXOG_HUMAN

UniProt Comments for ENDOGL1

ENDOGL1: Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity. Belongs to the DNA/RNA non-specific endonuclease family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Deoxyribonuclease; EC 3.1.30.-; Ribonuclease

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: nucleic acid binding; endonuclease activity; metal ion binding

Biological Process: DNA catabolic process, endonucleolytic
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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