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GIMAP5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6136769

GIMAP5 is a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GIMAP5, Monoclonal Antibody
Full Product Name
GIMAP5 (GTPase IMAP Family Member 5, Immunity-associated Nucleotide 4-like 1 Protein, IAN4L1, Immunity-associated Nucleotide 5 Protein, hIAN5, IAN-5, Immunity-associated Protein 3, IMAP3, FLJ11296) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1E10
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human GIMAP5.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
34,846 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (150434436..150440737). Location: 7q36.1
OMIM
608086
3D Structure
ModBase 3D Structure for Q96F15
Immunogen
Partial recombinant corresponding to aa186-285 from human GIMAP5 (NP_060854) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
AFNNWGSVEEQRQQQAELLAVIERLGREREGSFHSNDLFLDAQLLQRTGAGACQEDYRQYQAKVEWQVEKHKQELRENESNWAYKALLRVKHLMLLHYE
Conjugate
APC

Product Categories/Family for anti-GIMAP5 antibody

Applications Tested/Suitable for anti-GIMAP5 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-GIMAP5 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-GIMAP5 antibody

Western Blot detection against Immunogen (37kD).
Mouse Anti-GIMAP5 Monoclonal Antibody – Cat# MBS6136769

Immunoprecipitation (IP) of anti-GIMAP5 antibody

Immunoprecipitation of GIMAP5 transfected lysate using GIMAP5 monoclonal antibody and Protein A Magnetic Bead and immunoblotted with GIMAP5 rabbit polyclonal antibody.
Mouse Anti-GIMAP5 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS6136769

Testing Data of anti-GIMAP5 antibody

Detection limit for recombinant GST tagged GIMAP5 is 1ng/ml as a capture antibody.
Mouse Anti-GIMAP5 Monoclonal Antibody, Testing Data – Cat# MBS6136769

Other Notes

Small volumes of anti-GIMAP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GIMAP5 purchase

MBS6136769 is an antibody targeting GIMAP5. Also known as GIMAP5 (GTPase IMAP Family Member 5, Immunity-associated Nucleotide 4-like 1 Protein, IAN4L1, Immunity-associated Nucleotide 5 Protein, hIAN5, IAN-5, Immunity-associated Protein 3, IMAP3, FLJ11296) APC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GIMAP5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GTPase IMAP family member 5
NCBI Official Synonym Full Names
GTPase, IMAP family member 5
NCBI Official Symbol
GIMAP5
NCBI Official Synonym Symbols
IAN4; IAN5; IROD; IAN-5; IMAP3; HIMAP3; IAN4L1
UniProt Protein Name
GTPase IMAP family member 5
UniProt Synonym Protein Names
Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; IAN-5; hIAN5; Immunity-associated protein 3
Protein Family
UniProt Gene Name
GIMAP5
UniProt Synonym Gene Names
IAN4L1; IAN5; IMAP3; IAN-5; hIAN5
UniProt Entry Name
GIMA5_HUMAN
NCBI Protein Information
GTPase IMAP family member 5; immunity associated protein 3; immune associated nucleotide 4 like 1; immunity-associated nucleotide 5 protein; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5

NCBI Summary for GIMAP5

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010]
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UniProt Comments for GIMAP5

GIMAP5: Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence. Belongs to the IAN GTP-binding protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Apoptosis; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: mitochondrial outer membrane; lysosome; integral to membrane

Molecular Function: GTP binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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