• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LSS Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6137461

MBS6137461 is an antibody targeting LSS. Also known as LSS (Lanosterol Synthase, 2,3-epoxysqualene--lanosterol Cyclase, Oxidosqualene--lanosterol Cyclase, OSC, hOSC, FLJ25486, FLJ35015, FLJ39450, FLJ46393) APC. Reactive in Human. Host: Mouse. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LSS, Monoclonal Antibody
Full Product Name
LSS (Lanosterol Synthase, 2,3-epoxysqualene--lanosterol Cyclase, Oxidosqualene--lanosterol Cyclase, OSC, hOSC, FLJ25486, FLJ35015, FLJ39450, FLJ46393) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2E4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human LSS.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
82,199 Da
OMIM
600909
3D Structure
ModBase 3D Structure for P48449
Immunogen
Partial recombinant corresponding to aa633-732 from human LSS (NP_001001438) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
FESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP
Conjugate
APC

Product Categories/Family for anti-LSS antibody

Applications Tested/Suitable for anti-LSS antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-LSS antibody
IHC-P: 3ug/ml
Applications are based on unconjugated antibody.

Testing Data of anti-LSS antibody

Immunoperoxidase on formalin-fixed paraffin-embedded human placenta using 129243 (3ug/ml)
Mouse Anti-LSS Monoclonal Antibody – Cat# MBS6137461

Immunofluorescence (IF) of anti-LSS antibody

Immunofluorescence on HeLa cells using 129243 (10ug/ml).
Mouse Anti-LSS Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6137461

Other Notes

Small volumes of anti-LSS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LSS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lanosterol synthase isoform 1
NCBI Official Synonym Full Names
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
NCBI Official Symbol
LSS
NCBI Official Synonym Symbols
OSC; CTRCT44
UniProt Protein Name
Lanosterol synthase
UniProt Synonym Protein Names
2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC; hOSC
Protein Family
UniProt Gene Name
LSS
UniProt Synonym Gene Names
OSC; OSC; hOSC
UniProt Entry Name
ERG7_HUMAN
NCBI Protein Information
lanosterol synthase

NCBI Summary for LSS

The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000