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PTTG1IP Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6138532

PTTG1IP directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTTG1IP, Monoclonal Antibody
Full Product Name
PTTG1IP (Pituitary Tumor-transforming Gene 1 Protein-interacting Protein, Pituitary Tumor-transforming Gene Protein-binding Factor, PBF, PTTG-binding Factor, C21orf1, C21orf3) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4C11
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human PTTG1IP.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
603784
3D Structure
ModBase 3D Structure for P53801
Immunogen
Full length recombinant corresponding to aa1-180 from human PTTG1IP (AAH20983) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MAPGVARGPTPYWRLRLGGAALLLLLIPVAAAQEPPGAACSQNTNKTCEECLKNVSCLWCNTNKACLDYPVTSVLPPASLCKLSSARWGVCWVNFEALIITMSVVGGTLLLGIAICCCCCCRRKRSRKPDRSEEKAMREREERRIRQEERRAEMKTRHDEIRKKYGLFKEENPYARFENN
Conjugate
APC

Product Categories/Family for anti-PTTG1IP antibody

Applications Tested/Suitable for anti-PTTG1IP antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PTTG1IP antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PTTG1IP antibody

Western Blot detection against Immunogen (45.54kD).
Mouse Anti-PTTG1IP Monoclonal Antibody – Cat# MBS6138532

Western Blot (WB) of anti-PTTG1IP antibody

Western Blot analysis of PTTG1IP expression in transfected 293T cell line by PTTG1IP monoclonal antibody. Lane 1: PTTG1IP transfected lysate (20.3kD). Lane 2: Non-transfected lysate.
Mouse Anti-PTTG1IP Monoclonal Antibody, Western Blot (WB) – Cat# MBS6138532

Other Notes

Small volumes of anti-PTTG1IP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTTG1IP purchase

MBS6138532 is an antibody targeting PTTG1IP. Also known as PTTG1IP (Pituitary Tumor-transforming Gene 1 Protein-interacting Protein, Pituitary Tumor-transforming Gene Protein-binding Factor, PBF, PTTG-binding Factor, C21orf1, C21orf3) APC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PTTG1IP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens pituitary tumor-transforming 1 interacting protein, mRNA
NCBI Official Synonym Full Names
PTTG1 interacting protein
NCBI Official Symbol
PTTG1IP
NCBI Official Synonym Symbols
PBF; C21orf1; C21orf3
UniProt Protein Name
Pituitary tumor-transforming gene 1 protein-interacting protein
UniProt Synonym Protein Names
Pituitary tumor-transforming gene protein-binding factor
UniProt Gene Name
PTTG1IP
UniProt Synonym Gene Names
C21orf1; C21orf3; PBF
UniProt Entry Name
PTTG_HUMAN
NCBI Protein Information
pituitary tumor-transforming gene 1 protein-interacting protein

NCBI Summary for PTTG1IP

This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]
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UniProt Comments for PTTG1IP

PTTG1IP: May facilitate PTTG1 nuclear translocation.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: membrane; cytoplasm; integral to membrane; nucleus

Molecular Function: receptor activity

Biological Process: protein import into nucleus; multicellular organismal development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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