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SFRS3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6139012

MBS6139012 is an antibody targeting SFRS3. Also known as SFRS3 (Serine/Arginine-rich Splicing Factor 3, Pre-mRNA-splicing Factor SRP20, Splicing Factor, Arginine/Serine-rich 3, SRP20) APC. Reactive in Human, Mouse, Rat. Host: Mouse. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SFRS3, Monoclonal Antibody
Full Product Name
SFRS3 (Serine/Arginine-rich Splicing Factor 3, Pre-mRNA-splicing Factor SRP20, Splicing Factor, Arginine/Serine-rich 3, SRP20) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2D2
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human SFRS3. Species Crossreactivity: mouse and rat.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
Predicted: 18 kDa

Observed: 19 kDa
OMIM
603364
3D Structure
ModBase 3D Structure for P84103
Immunogen
Partial recombinant corresponding to aa1-86, from SFRS3 (NP_003008) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQ*
Conjugate
APC

Product Categories/Family for anti-SFRS3 antibody

Applications Tested/Suitable for anti-SFRS3 antibody
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-SFRS3 antibody
IF: 10ug/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SFRS3 antibody

Western Blot detection against Immunogen (35.09kD).
Mouse Anti-SFRS3 Monoclonal Antibody – Cat# MBS6139012

Western Blot (WB) of anti-SFRS3 antibody

SFRS3 monoclonal antibody. Western Blot analysis of SFRS3 expression in Raw 264.7
Mouse Anti-SFRS3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6139012

Western Blot (WB) of anti-SFRS3 antibody

SFRS3 monoclonal antibody. Western Blot analysis of SFRS3 expression in NIH/3T3
Mouse Anti-SFRS3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6139012

Immunofluorescence (IF) of anti-SFRS3 antibody

Immunofluorescence of monoclonal antibody to SFRS3 on HeLa cell. [antibody concentration 10ug/ml
Mouse Anti-SFRS3 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6139012

Testing Data of anti-SFRS3 antibody

Detection limit for recombinant GST tagged SFRS3 is ~0.1ng/ml as a capture antibody.
Mouse Anti-SFRS3 Monoclonal Antibody, Testing Data – Cat# MBS6139012

Other Notes

Small volumes of anti-SFRS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SFRS3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/arginine-rich splicing factor 3
NCBI Official Synonym Full Names
serine/arginine-rich splicing factor 3
NCBI Official Symbol
SRSF3
NCBI Official Synonym Symbols
SFRS3; SRp20
UniProt Protein Name
Serine/arginine-rich splicing factor 3
UniProt Synonym Protein Names
Pre-mRNA-splicing factor SRP20; Splicing factor, arginine/serine-rich 3
UniProt Gene Name
SRSF3
UniProt Synonym Gene Names
SFRS3; SRP20
UniProt Entry Name
SRSF3_HUMAN
NCBI Protein Information
serine/arginine-rich splicing factor 3; pre-mRNA-splicing factor SRP20; splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich, 20-kD

NCBI Summary for SFRS3

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010]
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UniProt Comments for SFRS3

SFRS3: May be involved in RNA processing in relation with cellular proliferation and/or maturation. Belongs to the splicing factor SR family.

Protein type: Spliceosome; RNA-binding; RNA processing; RNA splicing

Chromosomal Location of Human Ortholog: 6p21

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: protein binding; RNA binding; nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA export from nucleus; RNA splicing; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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