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SMS Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6139182

The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMS, Monoclonal Antibody
Full Product Name
SMS (Spermine Synthase, SPMSY, Spermidine Aminopropyltransferase) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1G6
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human SMS.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
35,278 Da
OMIM
182891
3D Structure
ModBase 3D Structure for P19623
Immunogen
Full length recombinant corresponding to aa1-367 from human SMS (AAH09898) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWKKAKP
Conjugate
APC

Product Categories/Family for anti-SMS antibody

Applications Tested/Suitable for anti-SMS antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-SMS antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SMS antibody

Western Blot detection against Immunogen (66.37kD).
Mouse Anti-SMS Monoclonal Antibody – Cat# MBS6139182

Western Blot (WB) of anti-SMS antibody

Western Blot analysis of SMS expression in transfected 293T cell line by SMS monoclonal antibody. Lane 1: SMS transfected lysate (41.268kD). Lane 2: Non-transfected lysate.
Mouse Anti-SMS Monoclonal Antibody, Western Blot (WB) – Cat# MBS6139182

Testing Data of anti-SMS antibody

Detection limit for recombinant GST tagged SMS is 0.03ng/ml as a capture antibody.
Mouse Anti-SMS Monoclonal Antibody, Testing Data – Cat# MBS6139182

Other Notes

Small volumes of anti-SMS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMS purchase

MBS6139182 is an antibody targeting SMS. Also known as SMS (Spermine Synthase, SPMSY, Spermidine Aminopropyltransferase) APC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SMS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens spermine synthase, mRNA
NCBI Official Synonym Full Names
spermine synthase
NCBI Official Symbol
SMS
NCBI Official Synonym Symbols
SRS; SpS; MRSR; SPMSY
UniProt Protein Name
Spermidine synthase
UniProt Synonym Protein Names
Putrescine aminopropyltransferase
Protein Family
UniProt Gene Name
SRM
UniProt Synonym Gene Names
SPS1; SRML1; SPDSY
UniProt Entry Name
SPEE_HUMAN
NCBI Protein Information
spermine synthase

NCBI Summary for SMS

This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
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UniProt Comments for SMS

SRM: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine. Belongs to the spermidine/spermine synthase family.

Protein type: Amino Acid Metabolism - arginine and proline; Other Amino Acids Metabolism - glutathione; EC 2.5.1.16; Amino Acid Metabolism - cysteine and methionine; Other Amino Acids Metabolism - beta-alanine; Transferase

Chromosomal Location of Human Ortholog: 1p36-p22

Cellular Component: cytosol

Molecular Function: protein homodimerization activity; spermidine synthase activity

Biological Process: spermidine biosynthetic process; polyamine metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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