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THAP1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6139492

MBS6139492 is an antibody targeting THAP1. Also known as THAP1 (THAP Domain-containing Protein 1, 4833431A01Rik, DYT6, FLJ10477, MGC33014) APC. Reactive in Human. Host: Mouse. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
THAP1, Monoclonal Antibody
Full Product Name
THAP1 (THAP Domain-containing Protein 1, 4833431A01Rik, DYT6, FLJ10477, MGC33014) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
2C1-2F2
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human THAP1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
6,493 Da
Immunogen
Full length recombinant corresponding to aa1-214 from human THAP1 (AAH21721) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFLCTEPHDKKEDLLEPQEQLPPPPLPPPVSQVDAAIGLLMPPLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLEQQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQKEKDDVSERGYVILPNDYFEIVEVPA
Conjugate
APC
Applications Tested/Suitable for anti-THAP1 antibody
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-THAP1 antibody
IF: 10ug/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-THAP1 antibody

Western Blot detection against Immunogen (49.54kD).
Mouse Anti-THAP1 Monoclonal Antibody – Cat# MBS6139492

Western Blot (WB) of anti-THAP1 antibody

Western Blot analysis of THAP1 expression in transfected 293T cell line by THAP1 monoclonal antibody. Lane 1: THAP1 transfected lysate (24.9kD). Lane 2: Non-transfected lysate.
Mouse Anti-THAP1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6139492

Immunofluorescence (IF) of anti-THAP1 antibody

Immunofluorescence of monoclonal antibody to THAP1 on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-THAP1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6139492

Western Blot (WB) of anti-THAP1 antibody

Western blot analysis of THAP1 over-expressed 293 cell line, cotransfected with THAP1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with THAP1 monoclonal antibody, GAPDH (36.1kD) used as specificity and loading control.
Mouse Anti-THAP1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6139492

Other Notes

Small volumes of anti-THAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for THAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens THAP domain containing, apoptosis associated protein 1, mRNA
NCBI Official Synonym Full Names
THAP domain containing 1
NCBI Official Symbol
THAP1
NCBI Official Synonym Symbols
DYT6
NCBI Protein Information
THAP domain-containing protein 1

NCBI Summary for THAP1

The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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