• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Monocarboxylate Transporter 3 (SLC16A8) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS614018

MBS614018 is an antibody targeting SLC16A8. Also known as Monocarboxylate Transporter 3 (MCT3, MOT3). Reactive in Rat. Host: Rabbit. More details

$965 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Monocarboxylate Transporter 3 (SLC16A8), Polyclonal Antibody
Full Product Name
Monocarboxylate Transporter 3 (MCT3, MOT3)
Product Gene Name
anti-SLC16A8 antibody
Product Synonym Names
Anti -Monocarboxylate Transporter 3 (MCT3, MOT3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, before the addition of glcerol to 40%.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes rat Monocarboxylate Transporter 3 (MCT3). The immunogen shows no significant sequence homology with other MCT. Species sequence homology: Mouse.
Preparation and Storage
For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
52,319 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (38474144..38479170, complement). Location: 22q12.3-q13.2
OMIM
610409
3D Structure
ModBase 3D Structure for O95907
Immunogen
A 19 amino acid peptide sequence near the C-terminus of rat MCT3 (1).

Product Categories/Family for anti-SLC16A8 antibody

Antibodies; Abs to Monocarboxylate Transporter
Applications Tested/Suitable for anti-SLC16A8 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SLC16A8 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:2500-1:25,000, using 50-100ng of control peptide/well
Western Blot (Chemiluminescence): 1-5ug/ml

Other Notes

Small volumes of anti-SLC16A8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC16A8. It may not necessarily be applicable to this product.

NCBI GI #
114796626
NCBI GeneID
23539
NCBI Accession #
NP_037488.2
UniProt Primary Accession #
O95907
UniProt Secondary Accession #
Q9UBE2
UniProt Related Accession #
O95907
GenBank Nucleotide #
NM_013356.2
NCBI Official Full Name
monocarboxylate transporter 3
NCBI Official Synonym Full Names
solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
NCBI Official Symbol
SLC16A8
NCBI Official Synonym Symbols
MCT3; REMP
UniProt Protein Name
Monocarboxylate transporter 3
UniProt Synonym Protein Names
Solute carrier family 16 member 8
Protein Family
Monocarboxylate transporter
UniProt Gene Name
SLC16A8
UniProt Synonym Gene Names
MCT3
UniProt Entry Name
MOT3_HUMAN
NCBI Protein Information
monocarboxylate transporter 3; MCT 3; OTTHUMP00000199351; solute carrier family 16 member 8; solute carrier 16 (monocarboxylic acid transporters), member 8

NCBI Summary for SLC16A8

SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM]

UniProt Comments for SLC16A8

SLC16A8: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q12.3-q13.2

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity

Biological Process: cellular metabolic process; lactate transport; blood coagulation; pyruvate metabolic process; transmembrane transport; leukocyte migration
Show more

Research Articles on SLC16A8

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLC16A8 antibody

 Products by Pathway  Pathway Diagram
 Basigin Interactions Pathway antibodies  Basigin Interactions Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Proton-coupled Monocarboxylate Transport Pathway antibodies  Proton-coupled Monocarboxylate Transport Pathway Diagram
 Pyruvate Metabolism Pathway antibodies  Pyruvate Metabolism Pathway Diagram
 Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway antibodies  Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Organs/Tissues associated with anti-SLC16A8 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with SLC16A8 and Eye
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000