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SMPDL3B Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6140374

Located on chromosome 1, this gene encodes for acid sphingomyelinase like phosphodiesterase 3b precursor protein. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMPDL3B, Monoclonal Antibody
Full Product Name
SMPDL3B (Acid Sphingomyelinase-like Phosphodiesterase 3b, ASM-like Phosphodiesterase 3b, ASML3B) (Biotin)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG3,k
Clone Number
5E12
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified
Specificity
Recognizes human SMPDL3B.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
3D Structure
ModBase 3D Structure for Q92485
Immunogen
Partial recombinant protein corresponding to aa274-372 from human SMPDL3B with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
FFGHHHTDSFRMLYDDAGVPISAMFITPGVTPWKTTLPGVVNGANNPAIRVFEYDRATLSLKVRSPAEARGGGWEGLKCITTFPHSQLIHLPLTTEPQE
Conjugate
Biotin
Applications Tested/Suitable for anti-SMPDL3B antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-SMPDL3B antibody
Applications are based on unconjugated antibody.

Testing Data of anti-SMPDL3B antibody

Detection limit for recombinant GST tagged SMPDL3B is 0.03ng/ml using MBS632955 as a capture antibody.
Mouse Anti-SMPDL3B Monoclonal Antibody – Cat# MBS6140374

Western Blot (WB) of anti-SMPDL3B antibody

Western Blot detection against Immunogen using MBS632955 (37kD).
Mouse Anti-SMPDL3B Monoclonal Antibody, Western Blot (WB) – Cat# MBS6140374

Other Notes

Small volumes of anti-SMPDL3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMPDL3B purchase

MBS6140374 is an antibody targeting SMPDL3B. Also known as SMPDL3B (Acid Sphingomyelinase-like Phosphodiesterase 3b, ASM-like Phosphodiesterase 3b, ASML3B) (Biotin). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SMPDL3B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
acid sphingomyelinase-like phosphodiesterase 3b isoform 2
UniProt Protein Name
Acid sphingomyelinase-like phosphodiesterase 3b
UniProt Gene Name
SMPDL3B
UniProt Synonym Gene Names
ASML3B
UniProt Entry Name
ASM3B_HUMAN

UniProt Comments for SMPDL3B

SMPDL3B: Belongs to the acid sphingomyelinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.-; Phosphodiesterase; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: extracellular space

Molecular Function: sphingomyelin phosphodiesterase activity; hydrolase activity, acting on glycosyl bonds

Biological Process: sphingomyelin catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SMPDL3B antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >6 publications with SMPDL3B and Kidney
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