• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ARHGEF11 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6140658

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARHGEF11, Monoclonal Antibody
Full Product Name
ARHGEF11 (Rho Guanine Nucleotide Exchange Factor 11, PDZ-RhoGEF, KIAA0380, DKFZp667F1223, GTRAP48) (Biotin)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2F4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human ARHGEF11.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Partial recombinant corresponding to aa651-750 from ARHGEF11 (AAH57394) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
RSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEATRLHQSASSSTSSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDTLLPHLLEDDLGQLSDLEPE
Conjugate
Biotin

Product Categories/Family for anti-ARHGEF11 antibody

Applications Tested/Suitable for anti-ARHGEF11 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ARHGEF11 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ARHGEF11 antibody

Western Blot detection against Immunogen (36.63kD).
Mouse Anti-ARHGEF11 Monoclonal Antibody – Cat# MBS6140658

Western Blot (WB) of anti-ARHGEF11 antibody

ARHGEF11 monoclonal antibody Western Blot analysis of ARHGEF11 expression in human colon.
Mouse Anti-ARHGEF11 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6140658

Testing Data of anti-ARHGEF11 antibody

Detection limit for recombinant GST tagged ARHGEF11 is ~0.3ng/ml as a capture antibody.
Mouse Anti-ARHGEF11 Monoclonal Antibody, Testing Data – Cat# MBS6140658

Other Notes

Small volumes of anti-ARHGEF11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARHGEF11 purchase

MBS6140658 is an antibody targeting ARHGEF11. Also known as ARHGEF11 (Rho Guanine Nucleotide Exchange Factor 11, PDZ-RhoGEF, KIAA0380, DKFZp667F1223, GTRAP48) (Biotin). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGEF11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens Rho guanine nucleotide exchange factor (GEF) 11, mRNA
NCBI Official Synonym Full Names
Rho guanine nucleotide exchange factor 11
NCBI Official Symbol
ARHGEF11
NCBI Official Synonym Symbols
GTRAP48; PDZ-RHOGEF
NCBI Protein Information
rho guanine nucleotide exchange factor 11

NCBI Summary for ARHGEF11

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000