Rabbit Anti-AHCTF1 Polyclonal Antibody – Cat# MBS614132

Western blot analysis of ELYS in HeLa nuclear extract (10ug and 20ug used in lanes 1 and 2, respectively) using MBS614132 at 0.5ug/ml. Chemiluminescence detection was used.

At Hook Containing Transcription Factor 1 (AHCTF1) Antibody – Rabbit Polyclonal

Name: AHCTF1 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS614132
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS614132

ELYS is a novel nuclear transcription factor expressed in embryonic haematopoietic tissues and plays a role in both early and mature haematopoietic events. More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AT Hook Containing Transcription Factor 1 (AHCTF1), Polyclonal Antibody

Full Product Name

AT Hook Containing Transcription Factor 1 (AHCTF1, DKFZp434N093, ELYS, MST108, MSTP108, TMBS62)

Product Gene Name

anti-AHCTF1 antibody

Product Synonym Names

Anti -AT Hook Containing Transcription Factor 1 (AHCTF1, DKFZp434N093, ELYS, MST108, MSTP108, TMBS62)

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse

Purity/Purification

Serum
Serum

Specificity

Species Crossreactivity: Human. Other species have not been tested. Reactivity with mouse is likely owing to identity between this ortholog and human at the site recognized by this antibody.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

252,498 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (247002400..247094726, complement). Location: 1q44

OMIM

610853

3D Structure

ModBase 3D Structure for Q8WYP5

Immunogen

A syntetic peptide.

Product Categories/Family for anti-AHCTF1 antibody

Antibodies; Abs to Transcription Factors

Applications Tested/Suitable for anti-AHCTF1 antibody

Western Blot (WB), Immunoprecipitation (IP)

Application Notes for anti-AHCTF1 antibody

Suitable for use in Western Blot and Immunoprecipitation.

Other Notes

Small volumes of anti-AHCTF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AHCTF1 purchase

MBS614132 is an antibody targeting AHCTF1. Also known as AT Hook Containing Transcription Factor 1 (AHCTF1, DKFZp434N093, ELYS, MST108, MSTP108, TMBS62). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AHCTF1. It may not necessarily be applicable to this product.

NCBI GI #

119597573

NCBI GeneID

25909

UniProt Primary Accession #

Q8WYP5

UniProt Secondary Accession #

Q7Z4E3; Q8IZA4; Q96EH9; Q9Y4Q6; A6NGM0; A8MSG9; A8MZ86

UniProt Related Accession #

Q8WYP5

NCBI Official Full Name

AT hook containing transcription factor 1, isoform CRA_c

NCBI Official Synonym Full Names

AT hook containing transcription factor 1

NCBI Official Symbol

AHCTF1

NCBI Official Synonym Symbols

ELYS; MST108; TMBS62; MSTP108; DKFZp434N093

UniProt Protein Name

Protein ELYS

UniProt Synonym Protein Names

Embryonic large molecule derived from yolk sac; Protein MEL-28; Putative AT-hook-containing transcription factor 1

UniProt Gene Name

AHCTF1

UniProt Synonym Gene Names

ELYS; TMBS62

UniProt Entry Name

ELYS_HUMAN

NCBI Protein Information

protein ELYS; OTTHUMP00000038418; OTTHUMP00000038419; ELYS transcription factor like protein TMBS62; ELYS transcription factor-like protein TMBS62; embryonic large molecule derived from yolk sac; putative AT-hook-containing transcription factor 1

UniProt Comments for AHCTF1

ELYS: Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis. Belongs to the ELYS family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: nucleoplasm; nuclear membrane; nuclear matrix; nuclear pore; nucleus; cytosol; chromatin

Molecular Function: DNA binding; transcription factor activity

Biological Process: nuclear pore complex assembly; protein transport; mRNA transport; regulation of transcription, DNA-dependent; cytokinesis; mitotic cell cycle

Research Articles on AHCTF1

1. Results suggets that ELYS is an unexpected member of the nuclear pore and kinetochore that functions in both pore assembly at the nucleus and faithful cell division.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-AHCTF1 antibody

Products by Pathway	Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
DNA Replication Pathway antibodies	DNA Replication Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Mitotic M-M/G1 Phases Pathway antibodies	Mitotic M-M/G1 Phases Pathway Diagram
Mitotic Prometaphase Pathway antibodies	Mitotic Prometaphase Pathway Diagram

Organs/Tissues associated with anti-AHCTF1 antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>1 publications with AHCTF1 and Embryonic Tissue
Bone Antibodies	>1 publications with AHCTF1 and Bone
Eye Antibodies	>1 publications with AHCTF1 and Eye
Thymus Antibodies	>1 publications with AHCTF1 and Thymus
Liver Antibodies	>1 publications with AHCTF1 and Liver
Bone Marrow Antibodies	>1 publications with AHCTF1 and Bone Marrow